| SP | Scherzer, M.Scherzer, Max † $ >> | 33 | 2017 | R | 95 | 19 | 19 | 10 | 5 | 3.31 | .276 | 1.10 | 6.7 | 3.3 | 9.2 | 127.2 | 94 | 51 | 47 | 16 | 47 | 130 | 2 | 0 | 0 | 1 | 15 | 5 | 2 | 3.82 |
| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 89 | 18 | 18 | 7 | 8 | 4.38 | .308 | 1.31 | 9.1 | 2.7 | 6.3 | 123.1 | 125 | 72 | 60 | 17 | 37 | 86 | 4 | 0 | 0 | 2 | 8 | 3 | 3 | 4.37 |
| SP | Adams, B.Adams, Babe $$ >> | 27 | 1909 | R | 86 | 18 | 18 | 5 | 4 | 5.04 | .314 | 1.37 | 9.5 | 2.8 | 5.2 | 100.0 | 106 | 65 | 56 | 15 | 31 | 58 | 1 | 0 | 0 | 1 | 5 | 0 | 1 | 4.72 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 17 | 17 | 7 | 6 | 6.31 | .362 | 1.66 | 11.7 | 3.3 | 4.8 | 102.2 | 133 | 77 | 72 | 17 | 37 | 54 | 2 | 0 | 0 | 1 | 5 | 5 | 3 | 5.34 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 17 | 17 | 6 | 7 | 5.68 | .324 | 1.42 | 10.0 | 2.8 | 6.2 | 114.0 | 127 | 80 | 72 | 24 | 35 | 78 | 3 | 0 | 0 | 0 | 6 | 2 | 1 | 5.34 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 33 | 0 | 2 | 4 | 2.94 | .308 | 1.31 | 8.7 | 3.3 | 7.9 | 33.2 | 32 | 11 | 11 | 2 | 12 | 29 | 0 | 22 | 1 | 0 | 0 | 1 | 0 | 3.21 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 39 | 0 | 3 | 2 | 5.61 | .323 | 1.43 | 9.8 | 3.1 | 6.5 | 43.1 | 47 | 31 | 27 | 6 | 15 | 31 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 26 | 0 | 3 | 0 | 1.27 | .254 | 0.99 | 4.5 | 4.5 | 9.6 | 28.1 | 14 | 5 | 4 | 1 | 14 | 30 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 2.93 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 3 | 0 | 1 | 0 | 8.10 | .286 | 1.20 | 9.0 | 3.0 | 6.0 | 3.1 | 3 | 3 | 3 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.33 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 17 | 0 | 1 | 1 | 3.26 | .301 | 1.29 | 7.1 | 4.7 | 9.9 | 19.1 | 15 | 8 | 7 | 2 | 10 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.74 |