| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 16 | 16 | 8 | 4 | 3.56 | .267 | 1.07 | 8.0 | 1.6 | 5.2 | 129.0 | 115 | 53 | 51 | 18 | 23 | 75 | 5 | 0 | 0 | 2 | 8 | 3 | 0 | 4.26 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 16 | 16 | 5 | 7 | 5.12 | .333 | 1.47 | 9.4 | 3.8 | 9.3 | 102.0 | 107 | 60 | 58 | 9 | 43 | 105 | 1 | 0 | 0 | 0 | 7 | 3 | 5 | 3.44 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 16 | 16 | 5 | 11 | 5.82 | .345 | 1.54 | 10.8 | 3.2 | 4.8 | 108.1 | 129 | 80 | 70 | 13 | 38 | 57 | 2 | 0 | 0 | 0 | 5 | 4 | 1 | 4.68 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 15 | 15 | 3 | 11 | 6.23 | .357 | 1.64 | 11.7 | 3.1 | 4.5 | 99.2 | 129 | 81 | 69 | 13 | 34 | 50 | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 4.82 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 45 | 0 | 1 | 4 | 3.04 | .256 | 1.03 | 7.4 | 2.0 | 9.7 | 50.1 | 41 | 18 | 17 | 5 | 11 | 54 | 0 | 5 | 2 | 0 | 0 | 0 | 2 | 2.80 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 29 | 0 | 2 | 0 | 2.80 | .259 | 0.99 | 6.9 | 2.1 | 8.2 | 35.1 | 27 | 11 | 11 | 3 | 8 | 32 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 3.14 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 18 | 0 | 0 | 0 | 1.96 | .258 | 1.04 | 5.5 | 3.9 | 7.8 | 23.0 | 14 | 5 | 5 | 3 | 10 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.26 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 6 | 1 | 2 | 1 | 4.20 | .297 | 1.27 | 8.4 | 3.0 | 5.4 | 15.0 | 14 | 8 | 7 | 2 | 5 | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.53 |