| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 98 | 34 | 34 | 12 | 15 | 2.99 | .281 | 1.16 | 7.4 | 3.1 | 7.5 | 273.2 | 225 | 98 | 91 | 23 | 93 | 228 | 14 | 0 | 0 | 1 | 22 | 3 | 3 | 3.48 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 33 | 33 | 7 | 15 | 5.48 | .350 | 1.56 | 10.6 | 3.5 | 4.7 | 174.0 | 204 | 120 | 106 | 30 | 68 | 90 | 0 | 0 | 0 | 0 | 8 | 9 | 5 | 5.53 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 32 | 11 | 15 | 4.51 | .313 | 1.33 | 8.9 | 3.1 | 5.1 | 217.1 | 215 | 119 | 109 | 25 | 75 | 123 | 2 | 0 | 0 | 1 | 19 | 7 | 2 | 4.50 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 32 | 32 | 9 | 21 | 5.07 | .318 | 1.38 | 9.7 | 2.8 | 4.4 | 246.2 | 264 | 153 | 139 | 27 | 76 | 121 | 10 | 0 | 0 | 0 | 11 | 5 | 3 | 4.43 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 7 | 14 | 4.44 | .333 | 1.47 | 10.0 | 3.3 | 5.9 | 213.0 | 236 | 120 | 105 | 31 | 78 | 139 | 3 | 0 | 0 | 0 | 19 | 5 | 7 | 4.76 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 82 | 0 | 5 | 3 | 2.93 | .262 | 1.04 | 6.8 | 2.5 | 9.9 | 104.1 | 79 | 37 | 34 | 9 | 29 | 114 | 0 | 9 | 6 | 0 | 0 | 3 | 4 | 2.86 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 56 | 0 | 3 | 6 | 4.12 | .352 | 1.59 | 8.0 | 6.5 | 9.0 | 54.2 | 48 | 25 | 25 | 5 | 39 | 54 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 4.48 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 38 | 0 | 5 | 1 | 2.59 | .256 | 1.03 | 6.6 | 2.9 | 9.0 | 41.2 | 30 | 12 | 12 | 2 | 13 | 41 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 2.59 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |