| SP | Skubal, T.Skubal, Tarik † $$ >> | 28 | 2025 | L | 100 | 33 | 33 | 19 | 7 | 2.05 | .228 | 0.89 | 6.5 | 1.5 | 10.8 | 241.1 | 175 | 59 | 55 | 21 | 39 | 289 | 4 | 0 | 0 | 2 | 26 | 0 | 2 | 2.22 |
| SP | Peralta, F.Peralta, Freddy >> | 29 | 2025 | R | 88 | 32 | 32 | 4 | 4 | 3.15 | .286 | 1.17 | 7.3 | 3.3 | 10.4 | 151.2 | 122 | 55 | 53 | 17 | 56 | 175 | 0 | 0 | 0 | 0 | 2 | 4 | 1 | 3.34 |
| SP | Kelly, M.Kelly, Merrill # >> | 36 | 2025 | R | 74 | 31 | 31 | 12 | 6 | 3.95 | .283 | 1.18 | 8.1 | 2.4 | 6.9 | 148.0 | 134 | 66 | 65 | 15 | 40 | 114 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 3.61 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 82 | 31 | 31 | 9 | 6 | 4.75 | .319 | 1.36 | 10.0 | 2.3 | 10.9 | 138.1 | 153 | 75 | 73 | 26 | 35 | 167 | 0 | 0 | 0 | 0 | 6 | 6 | 2 | 3.92 |
| SP | Littell, Z.Littell, Zack # >> | 29 | 2025 | R | 64 | 32 | 30 | 4 | 12 | 6.95 | .337 | 1.49 | 10.1 | 3.4 | 7.9 | 110.0 | 123 | 87 | 85 | 19 | 41 | 96 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 4.73 |
| CL | Hader, J.Hader, Josh † >> | 31 | 2025 | L | 100 | 72 | 0 | 7 | 2 | 1.64 | .222 | 0.83 | 5.1 | 2.3 | 11.2 | 77.0 | 44 | 16 | 14 | 4 | 20 | 96 | 0 | 39 | 2 | 0 | 0 | 2 | 0 | 2.04 |
| SU | Keller, B.Keller, Brad >> | 29 | 2025 | R | 90 | 74 | 0 | 5 | 0 | 2.07 | .286 | 1.15 | 6.3 | 4.0 | 10.4 | 78.1 | 55 | 18 | 18 | 3 | 35 | 90 | 0 | 6 | 3 | 0 | 0 | 4 | 2 | 2.69 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 78 | 91 | 0 | 4 | 7 | 3.49 | .309 | 1.31 | 7.9 | 3.9 | 8.1 | 118.2 | 104 | 47 | 46 | 13 | 51 | 106 | 0 | 0 | 4 | 0 | 0 | 4 | 3 | 4.03 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 69 | 83 | 0 | 6 | 1 | 3.40 | .262 | 1.03 | 7.8 | 1.5 | 7.3 | 84.2 | 73 | 37 | 32 | 14 | 14 | 68 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 4.15 |
| RP | Estevez, C.Estevez, Carlos >> | 32 | 2025 | R | 70 | 70 | 0 | 5 | 4 | 3.72 | .312 | 1.33 | 8.4 | 3.6 | 7.8 | 65.1 | 61 | 30 | 27 | 5 | 26 | 56 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.57 |
| RP | Iglesias, R.Iglesias, Raisel † >> | 35 | 2025 | R | 79 | 70 | 0 | 20 | 2 | 4.16 | .288 | 1.20 | 8.5 | 2.3 | 9.4 | 97.1 | 92 | 48 | 45 | 13 | 25 | 101 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.46 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 63 | 67 | 0 | 5 | 1 | 2.93 | .270 | 1.04 | 6.6 | 2.8 | 9.0 | 61.1 | 45 | 20 | 20 | 8 | 19 | 61 | 0 | 3 | 0 | 0 | 0 | 4 | 1 | 3.84 |
| RP | Mattson, I.Mattson, Isaac >> | 29 | 2025 | R | 64 | 56 | 0 | 4 | 1 | 3.13 | .333 | 1.48 | 8.8 | 4.7 | 8.2 | 54.2 | 53 | 21 | 19 | 4 | 28 | 49 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.76 |