| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 24 | 24 | 5 | 12 | 4.91 | .297 | 1.23 | 7.6 | 3.4 | 8.1 | 154.0 | 130 | 84 | 84 | 19 | 59 | 139 | 2 | 0 | 0 | 0 | 10 | 6 | 2 | 4.06 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 23 | 23 | 10 | 9 | 4.85 | .300 | 1.25 | 8.8 | 2.5 | 7.4 | 148.1 | 145 | 83 | 80 | 21 | 41 | 121 | 4 | 0 | 0 | 2 | 12 | 5 | 5 | 4.14 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 23 | 23 | 6 | 12 | 4.95 | .331 | 1.43 | 9.9 | 3.1 | 3.9 | 156.1 | 171 | 90 | 86 | 18 | 53 | 67 | 4 | 0 | 0 | 0 | 11 | 8 | 3 | 4.81 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 23 | 23 | 5 | 13 | 5.19 | .350 | 1.56 | 8.6 | 5.4 | 8.3 | 111.0 | 106 | 67 | 64 | 15 | 67 | 102 | 0 | 0 | 0 | 0 | 3 | 6 | 1 | 4.89 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 61 | 0 | 4 | 3 | 4.39 | .314 | 1.33 | 8.2 | 3.8 | 8.0 | 92.1 | 84 | 47 | 45 | 13 | 39 | 82 | 0 | 9 | 2 | 0 | 0 | 4 | 0 | 4.46 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 53 | 0 | 2 | 5 | 3.44 | .300 | 1.26 | 8.0 | 3.5 | 8.6 | 70.2 | 62 | 30 | 27 | 10 | 27 | 67 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 4.19 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 40 | 0 | 2 | 1 | 3.73 | .317 | 1.32 | 6.6 | 5.3 | 6.8 | 41.0 | 30 | 20 | 17 | 4 | 24 | 31 | 0 | 4 | 2 | 0 | 0 | 3 | 0 | 4.73 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 34 | 0 | 1 | 2 | 3.54 | .269 | 1.11 | 5.4 | 4.7 | 9.9 | 40.2 | 24 | 16 | 16 | 4 | 21 | 44 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.68 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 30 | 0 | 3 | 1 | 6.09 | .346 | 1.59 | 10.6 | 3.7 | 4.0 | 34.0 | 40 | 28 | 23 | 7 | 14 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.03 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 14 | 0 | 0 | 0 | 6.75 | .365 | 1.73 | 9.0 | 6.9 | 9.7 | 13.1 | 13 | 10 | 10 | 0 | 10 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.15 |