| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 25 | 25 | 12 | 8 | 2.49 | .248 | 0.98 | 7.4 | 1.4 | 5.0 | 195.0 | 160 | 64 | 54 | 16 | 31 | 108 | 5 | 0 | 0 | 3 | 17 | 2 | 0 | 3.47 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 93 | 24 | 24 | 10 | 9 | 4.12 | .304 | 1.27 | 8.9 | 2.5 | 5.3 | 164.0 | 163 | 81 | 75 | 20 | 46 | 96 | 5 | 0 | 0 | 2 | 12 | 6 | 1 | 4.37 |
| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 24 | 24 | 14 | 2 | 3.17 | .271 | 1.10 | 6.4 | 3.6 | 8.2 | 164.2 | 116 | 63 | 58 | 13 | 65 | 150 | 2 | 0 | 0 | 2 | 17 | 3 | 4 | 3.45 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 24 | 24 | 8 | 10 | 5.58 | .331 | 1.44 | 9.9 | 3.1 | 5.6 | 153.1 | 168 | 103 | 95 | 20 | 53 | 95 | 6 | 0 | 0 | 1 | 9 | 7 | 5 | 4.63 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 23 | 23 | 7 | 7 | 5.84 | .306 | 1.28 | 9.5 | 2.0 | 4.4 | 148.0 | 157 | 96 | 96 | 23 | 33 | 72 | 2 | 0 | 0 | 0 | 8 | 6 | 4 | 4.84 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 49 | 0 | 6 | 3 | 3.44 | .283 | 1.15 | 8.1 | 2.3 | 7.6 | 52.1 | 47 | 20 | 20 | 4 | 13 | 44 | 0 | 23 | 4 | 0 | 0 | 2 | 2 | 3.17 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 56 | 0 | 4 | 4 | 4.72 | .272 | 1.10 | 7.9 | 2.1 | 9.8 | 55.1 | 48 | 29 | 29 | 7 | 13 | 60 | 0 | 1 | 3 | 0 | 0 | 1 | 4 | 3.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 28 | 0 | 2 | 1 | 3.45 | .344 | 1.53 | 9.6 | 4.5 | 10.0 | 28.2 | 30 | 13 | 11 | 2 | 14 | 31 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 3.32 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 31 | 0 | 4 | 2 | 3.15 | .283 | 1.18 | 7.2 | 3.6 | 6.6 | 45.2 | 36 | 17 | 16 | 6 | 18 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.47 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 14 | 0 | 1 | 0 | 3.65 | .278 | 1.14 | 8.8 | 1.5 | 6.6 | 49.1 | 48 | 20 | 20 | 6 | 8 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.67 |