| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 19 | 19 | 11 | 5 | 2.73 | .287 | 1.17 | 6.9 | 3.7 | 7.0 | 155.0 | 119 | 47 | 47 | 10 | 63 | 120 | 4 | 0 | 0 | 0 | 16 | 5 | 1 | 3.61 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 18 | 18 | 7 | 5 | 5.13 | .331 | 1.45 | 10.0 | 3.1 | 5.7 | 121.0 | 134 | 72 | 69 | 16 | 42 | 77 | 3 | 0 | 0 | 0 | 6 | 4 | 2 | 4.59 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 18 | 18 | 5 | 7 | 5.35 | .330 | 1.46 | 9.2 | 4.1 | 7.2 | 117.2 | 119 | 78 | 70 | 18 | 53 | 94 | 5 | 0 | 0 | 1 | 9 | 2 | 3 | 4.80 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 18 | 17 | 6 | 6 | 5.66 | .345 | 1.58 | 9.5 | 4.7 | 8.7 | 103.1 | 109 | 67 | 65 | 17 | 54 | 99 | 0 | 0 | 0 | 0 | 6 | 0 | 3 | 4.80 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 53 | 0 | 1 | 2 | 2.77 | .267 | 1.06 | 5.8 | 3.7 | 10.2 | 65.0 | 42 | 22 | 20 | 3 | 27 | 74 | 0 | 8 | 1 | 0 | 0 | 2 | 4 | 2.66 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 36 | 0 | 3 | 4 | 3.56 | .291 | 1.23 | 9.2 | 1.9 | 9.2 | 43.0 | 44 | 20 | 17 | 9 | 9 | 44 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.30 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 26 | 0 | 5 | 1 | 1.65 | .315 | 1.38 | 4.5 | 8.2 | 9.3 | 32.2 | 16 | 6 | 6 | 0 | 29 | 33 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 3.66 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 22 | 0 | 4 | 5 | 5.26 | .342 | 1.56 | 9.4 | 5.0 | 8.3 | 25.2 | 26 | 15 | 15 | 4 | 14 | 23 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 4.92 |