| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 8 | 8 | 1 | 4 | 4.44 | .288 | 1.21 | 8.8 | 2.3 | 7.7 | 48.2 | 47 | 26 | 24 | 12 | 12 | 41 | 1 | 0 | 0 | 0 | 5 | 0 | 0 | 5.29 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 8 | 8 | 3 | 4 | 3.65 | .303 | 1.31 | 9.5 | 2.4 | 9.2 | 56.2 | 59 | 23 | 23 | 9 | 15 | 57 | 2 | 0 | 0 | 1 | 6 | 0 | 2 | 3.86 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 8 | 8 | 5 | 2 | 2.56 | .281 | 1.16 | 7.3 | 3.2 | 9.0 | 59.2 | 48 | 17 | 17 | 2 | 21 | 59 | 1 | 0 | 0 | 1 | 7 | 1 | 2 | 2.56 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 6 | 6 | 2 | 2 | 4.30 | .323 | 1.43 | 9.5 | 3.6 | 4.4 | 37.2 | 39 | 21 | 18 | 5 | 15 | 18 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 5.00 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 22 | 0 | 2 | 2 | 4.02 | .324 | 1.44 | 7.0 | 6.1 | 9.6 | 31.1 | 24 | 14 | 14 | 2 | 21 | 33 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 3 | 0 | 1 | 0 | 0.00 | .154 | 0.55 | 3.0 | 3.0 | 15.0 | 3.2 | 1 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0.67 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 3 | 0 | 0 | 1 | 2.45 | .353 | 1.36 | 6.0 | 9.0 | 15.0 | 3.2 | 2 | 1 | 1 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.00 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 2 | 0 | 0 | 0 | 0.00 | .143 | 0.50 | 0.0 | 4.5 | 13.5 | 2.0 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.50 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 3 | 0 | 0 | 0 | 5.40 | .286 | 1.20 | 6.0 | 6.0 | 3.0 | 3.1 | 2 | 2 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.33 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 5 | 1 | 2 | 0 | 2.66 | .268 | 1.10 | 6.3 | 3.9 | 5.5 | 23.2 | 16 | 8 | 7 | 1 | 10 | 14 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.65 |