| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 95 | 10 | 10 | 5 | 3 | 3.67 | .275 | 1.09 | 7.7 | 2.3 | 11.1 | 68.2 | 58 | 28 | 28 | 4 | 17 | 84 | 1 | 0 | 0 | 0 | 5 | 3 | 2 | 2.18 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 80 | 10 | 10 | 5 | 2 | 5.52 | .347 | 1.53 | 11.3 | 2.5 | 6.8 | 62.0 | 78 | 38 | 38 | 9 | 17 | 47 | 0 | 0 | 0 | 0 | 4 | 4 | 0 | 4.39 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 70 | 10 | 10 | 0 | 5 | 6.67 | .382 | 1.76 | 12.4 | 3.7 | 6.1 | 56.2 | 77 | 42 | 42 | 15 | 23 | 38 | 0 | 0 | 0 | 0 | 3 | 5 | 3 | 6.63 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 9 | 9 | 1 | 4 | 6.84 | .360 | 1.69 | 12.8 | 2.6 | 8.1 | 52.2 | 74 | 40 | 40 | 9 | 15 | 47 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 4.31 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 21 | 0 | 1 | 2 | 2.05 | .327 | 1.45 | 11.5 | 1.6 | 11.9 | 22.0 | 28 | 5 | 5 | 2 | 4 | 29 | 0 | 10 | 2 | 0 | 0 | 0 | 0 | 2.09 |
| SU | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 88 | 28 | 0 | 1 | 2 | 4.31 | .309 | 1.31 | 7.5 | 4.4 | 11.6 | 31.1 | 26 | 15 | 15 | 3 | 15 | 40 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.23 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 78 | 29 | 0 | 2 | 2 | 3.34 | .265 | 1.05 | 7.3 | 2.3 | 9.3 | 32.1 | 26 | 12 | 12 | 2 | 8 | 33 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 2.59 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 15 | 0 | 2 | 2 | 2.93 | .352 | 1.63 | 8.4 | 6.6 | 7.2 | 15.1 | 14 | 6 | 5 | 2 | 11 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| RP | O'Day, D.O'Day, Darren >> | 32 | 2014 | R | 65 | 12 | 0 | 1 | 0 | 2.35 | .246 | 0.98 | 6.0 | 3.0 | 9.0 | 15.1 | 10 | 4 | 4 | 1 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.87 |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 63 | 9 | 0 | 1 | 0 | 2.31 | .222 | 0.86 | 3.3 | 4.9 | 8.2 | 11.2 | 4 | 3 | 3 | 0 | 6 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.82 |