| SP | Arrieta, J.Arrieta, Jake † $ >> | 29 | 2015 | R | 95 | 36 | 36 | 15 | 14 | 2.91 | .263 | 1.05 | 7.3 | 2.1 | 9.0 | 256.1 | 207 | 84 | 83 | 24 | 61 | 255 | 7 | 0 | 0 | 2 | 26 | 6 | 5 | 3.01 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 34 | 34 | 12 | 14 | 4.15 | .305 | 1.29 | 8.1 | 3.5 | 6.4 | 219.0 | 198 | 106 | 101 | 31 | 84 | 156 | 2 | 0 | 0 | 0 | 18 | 7 | 6 | 4.66 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 79 | 33 | 33 | 9 | 16 | 3.06 | .273 | 1.08 | 6.7 | 3.0 | 9.1 | 226.1 | 168 | 80 | 77 | 26 | 76 | 229 | 5 | 0 | 0 | 2 | 23 | 11 | 4 | 3.62 |
| SP | Clevinger, M.Clevinger, Mike >> | 28 | 2019 | R | 74 | 33 | 33 | 7 | 7 | 5.02 | .319 | 1.36 | 8.7 | 3.6 | 10.2 | 179.1 | 173 | 101 | 100 | 26 | 71 | 202 | 0 | 0 | 0 | 0 | 15 | 8 | 0 | 3.96 |
| RP | Kimbrel, C.Kimbrel, Craig $ >> | 29 | 2017 | R | 100 | 91 | 0 | 6 | 5 | 3.49 | .284 | 1.16 | 7.8 | 2.7 | 10.3 | 118.2 | 102 | 46 | 46 | 11 | 36 | 135 | 0 | 5 | 6 | 0 | 0 | 3 | 5 | 2.92 |
| RP | Boxberger, B.Boxberger, Brad # >> | 26 | 2014 | R | 87 | 83 | 0 | 4 | 8 | 4.67 | .300 | 1.29 | 7.9 | 3.8 | 11.6 | 88.2 | 77 | 48 | 46 | 17 | 37 | 113 | 0 | 10 | 7 | 0 | 0 | 0 | 1 | 4.20 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 62 | 0 | 6 | 3 | 4.00 | .303 | 1.24 | 8.3 | 2.9 | 10.0 | 63.0 | 58 | 28 | 28 | 11 | 20 | 70 | 0 | 4 | 7 | 0 | 0 | 4 | 3 | 4.19 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 34 | 0 | 4 | 2 | 3.79 | .287 | 1.21 | 7.5 | 3.6 | 13.1 | 35.2 | 29 | 15 | 15 | 7 | 14 | 51 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.89 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 55 | 24 | 0 | 8 | 5 | 3.90 | .305 | 1.29 | 8.5 | 3.2 | 9.0 | 99.1 | 93 | 43 | 43 | 10 | 35 | 99 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 3.46 |