| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 31 | 31 | 12 | 14 | 4.20 | .279 | 1.16 | 8.9 | 1.6 | 8.3 | 240.0 | 236 | 116 | 112 | 37 | 42 | 220 | 7 | 0 | 0 | 2 | 14 | 1 | 7 | 3.71 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 30 | 30 | 14 | 11 | 5.04 | .335 | 1.49 | 9.8 | 3.6 | 8.1 | 196.1 | 213 | 112 | 110 | 29 | 79 | 177 | 0 | 0 | 0 | 0 | 13 | 5 | 7 | 4.40 |
| SP | Alexander, P.Alexander, Pete # >> | 28 | 1915 | R | 88 | 29 | 29 | 14 | 10 | 4.14 | .296 | 1.22 | 8.3 | 2.8 | 5.1 | 210.2 | 193 | 101 | 97 | 18 | 65 | 120 | 5 | 0 | 0 | 2 | 17 | 8 | 3 | 4.01 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 74 | 0 | 2 | 2 | 3.61 | .283 | 1.18 | 7.8 | 2.9 | 9.4 | 89.2 | 77 | 36 | 36 | 11 | 29 | 93 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 3.49 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 64 | 0 | 2 | 4 | 3.18 | .275 | 1.13 | 5.9 | 4.3 | 8.5 | 73.2 | 48 | 26 | 26 | 8 | 35 | 69 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.01 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 29 | 0 | 2 | 1 | 4.39 | .316 | 1.39 | 9.0 | 3.8 | 6.9 | 26.2 | 26 | 14 | 13 | 2 | 11 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.73 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 17 | 0 | 2 | 1 | 1.57 | .242 | 0.96 | 5.1 | 3.5 | 10.2 | 23.0 | 13 | 4 | 4 | 1 | 9 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.48 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 25 | 0 | 3 | 2 | 4.39 | .292 | 1.20 | 6.9 | 4.2 | 4.8 | 26.2 | 20 | 13 | 13 | 3 | 12 | 14 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 4.92 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 6 | 6 | 1 | 3 | 10.68 | .435 | 2.27 | 15.0 | 5.7 | 3.6 | 30.1 | 50 | 36 | 36 | 5 | 19 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.37 |
| CL | Devine, J.Devine, Joey † >> | 25 | 2008 | R | 81 | 48 | 0 | 2 | 2 | 4.60 | .335 | 1.49 | 8.6 | 4.8 | 6.9 | 47.0 | 45 | 27 | 24 | 7 | 25 | 36 | 0 | 34 | 10 | 0 | 0 | 1 | 0 | 5.06 |