| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 31 | 31 | 11 | 12 | 3.52 | .285 | 1.18 | 7.5 | 3.2 | 8.4 | 207.0 | 172 | 95 | 81 | 18 | 73 | 194 | 2 | 0 | 0 | 1 | 20 | 3 | 2 | 3.36 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 30 | 30 | 9 | 16 | 5.77 | .352 | 1.61 | 10.8 | 3.6 | 4.6 | 185.2 | 223 | 129 | 119 | 28 | 75 | 95 | 2 | 0 | 0 | 0 | 13 | 5 | 4 | 5.24 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 29 | 29 | 1 | 13 | 7.46 | .379 | 1.78 | 10.4 | 5.7 | 10.0 | 130.1 | 150 | 112 | 108 | 19 | 82 | 144 | 0 | 0 | 0 | 0 | 3 | 7 | 3 | 4.74 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 29 | 29 | 11 | 11 | 4.48 | .316 | 1.38 | 9.2 | 3.3 | 5.8 | 188.2 | 192 | 97 | 94 | 27 | 68 | 122 | 3 | 0 | 0 | 1 | 16 | 2 | 3 | 4.69 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 81 | 0 | 3 | 5 | 3.64 | .279 | 1.12 | 6.6 | 3.5 | 10.0 | 116.1 | 85 | 53 | 47 | 12 | 45 | 129 | 0 | 7 | 6 | 0 | 0 | 5 | 4 | 3.41 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 76 | 75 | 0 | 5 | 6 | 4.89 | .283 | 1.18 | 8.1 | 2.6 | 8.9 | 95.2 | 86 | 58 | 52 | 23 | 27 | 94 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 5.02 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 48 | 0 | 2 | 0 | 4.14 | .351 | 1.60 | 10.0 | 4.6 | 9.8 | 45.2 | 50 | 21 | 21 | 8 | 23 | 49 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.73 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 27 | 0 | 2 | 3 | 3.50 | .291 | 1.23 | 7.8 | 3.3 | 2.9 | 46.1 | 40 | 18 | 18 | 6 | 17 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.15 |