| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 31 | 31 | 8 | 21 | 4.35 | .286 | 1.18 | 8.1 | 2.5 | 8.3 | 240.0 | 217 | 120 | 116 | 34 | 66 | 221 | 14 | 0 | 0 | 2 | 15 | 5 | 3 | 3.89 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 84 | 30 | 30 | 8 | 10 | 4.97 | .304 | 1.29 | 9.1 | 2.6 | 5.3 | 168.1 | 169 | 96 | 93 | 30 | 48 | 98 | 0 | 0 | 0 | 0 | 12 | 4 | 2 | 5.08 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 30 | 6 | 15 | 5.74 | .341 | 1.53 | 9.3 | 4.4 | 5.5 | 196.0 | 203 | 131 | 125 | 31 | 96 | 120 | 2 | 0 | 0 | 0 | 12 | 5 | 3 | 5.38 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 78 | 0 | 3 | 6 | 3.04 | .280 | 1.14 | 7.7 | 2.6 | 11.3 | 103.2 | 88 | 39 | 35 | 11 | 30 | 129 | 0 | 4 | 5 | 0 | 0 | 3 | 3 | 2.84 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 75 | 0 | 7 | 5 | 3.75 | .277 | 1.11 | 8.4 | 1.7 | 8.2 | 98.1 | 91 | 43 | 41 | 17 | 18 | 89 | 0 | 5 | 2 | 0 | 0 | 4 | 3 | 4.11 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 53 | 0 | 4 | 4 | 3.29 | .303 | 1.27 | 9.0 | 2.4 | 10.1 | 63.0 | 63 | 24 | 23 | 9 | 17 | 71 | 0 | 8 | 4 | 0 | 0 | 2 | 2 | 3.51 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 14 | 0 | 0 | 1 | 7.17 | .366 | 1.73 | 11.1 | 4.7 | 4.3 | 21.1 | 26 | 17 | 17 | 4 | 11 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 6.10 |