| SP | Darvish, Y.Darvish, Yu † >> | 35 | 2022 | R | 100 | 34 | 34 | 17 | 7 | 3.15 | .279 | 1.14 | 7.1 | 3.2 | 8.3 | 240.0 | 189 | 94 | 84 | 21 | 85 | 220 | 2 | 0 | 0 | 0 | 24 | 5 | 6 | 3.43 |
| SP | Corbin, P.Corbin, Patrick >> | 29 | 2019 | L | 89 | 34 | 34 | 14 | 14 | 3.23 | .303 | 1.29 | 8.6 | 3.1 | 8.3 | 217.1 | 207 | 87 | 78 | 14 | 74 | 199 | 0 | 0 | 0 | 0 | 19 | 2 | 3 | 3.06 |
| SP | Suggs, G.Suggs, George >> | 28 | 1910 | R | 78 | 31 | 31 | 13 | 16 | 3.54 | .300 | 1.25 | 9.2 | 2.1 | 4.2 | 233.2 | 238 | 105 | 92 | 12 | 55 | 108 | 15 | 0 | 0 | 2 | 18 | 8 | 5 | 3.55 |
| SP | Patrick, C.Patrick, Chad >> | 26 | 2025 | R | 70 | 32 | 32 | 6 | 9 | 4.58 | .343 | 1.55 | 10.7 | 3.2 | 8.9 | 139.2 | 166 | 74 | 71 | 10 | 50 | 137 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 3.11 |
| SP | Manning, R.Manning, Rube >> | 26 | 1909 | R | 67 | 31 | 31 | 5 | 18 | 7.30 | .367 | 1.69 | 12.2 | 3.0 | 4.2 | 172.2 | 234 | 152 | 140 | 23 | 58 | 80 | 1 | 0 | 0 | 1 | 7 | 8 | 3 | 4.96 |
| RP | Rivera, M.Rivera, Mariano >> | 30 | 1999 | R | 93 | 103 | 0 | 8 | 4 | 3.63 | .314 | 1.37 | 8.5 | 3.9 | 5.9 | 111.2 | 105 | 49 | 45 | 7 | 48 | 73 | 0 | 1 | 3 | 0 | 0 | 0 | 5 | 3.80 |
| RP | Karsay, S.Karsay, Steve >> | 29 | 2001 | R | 72 | 100 | 0 | 3 | 5 | 3.48 | .274 | 1.13 | 7.5 | 2.8 | 6.4 | 113.2 | 94 | 47 | 44 | 6 | 35 | 80 | 0 | 17 | 2 | 0 | 0 | 0 | 4 | 3.20 |
| RP | Gregerson, L.Gregerson, Luke >> | 25 | 2009 | R | 59 | 65 | 0 | 2 | 3 | 2.06 | .281 | 1.14 | 7.1 | 3.2 | 8.7 | 70.0 | 55 | 19 | 16 | 4 | 25 | 68 | 0 | 7 | 2 | 0 | 0 | 2 | 0 | 2.96 |
| RP | Ramirez, E.Ramirez, Erasmo >> | 28 | 2004 | L | 50 | 110 | 0 | 9 | 1 | 2.81 | .272 | 1.08 | 8.0 | 1.6 | 5.2 | 93.0 | 83 | 29 | 29 | 14 | 17 | 54 | 0 | 8 | 3 | 0 | 0 | 4 | 1 | 4.47 |
| RP | Stoddard, T.Stoddard, Tim >> | 33 | 1986 | R | 48 | 50 | 0 | 3 | 5 | 4.29 | .312 | 1.35 | 7.1 | 5.1 | 6.5 | 71.1 | 56 | 37 | 34 | 5 | 40 | 51 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 4.21 |