| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 98 | 27 | 27 | 14 | 9 | 4.08 | .292 | 1.22 | 7.8 | 3.2 | 10.8 | 170.0 | 147 | 83 | 77 | 18 | 61 | 204 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.09 |
| SP | Bumgarner, M.Bumgarner, Madison >> | 23 | 2013 | L | 79 | 26 | 26 | 13 | 9 | 4.46 | .336 | 1.49 | 9.7 | 3.8 | 6.7 | 161.1 | 173 | 88 | 80 | 18 | 68 | 120 | 0 | 0 | 0 | 0 | 11 | 4 | 3 | 4.30 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 63 | 26 | 26 | 14 | 9 | 5.00 | .341 | 1.51 | 9.8 | 3.7 | 7.4 | 162.0 | 177 | 96 | 90 | 30 | 67 | 134 | 5 | 0 | 0 | 3 | 12 | 8 | 3 | 5.14 |
| SP | Castillo, L.Castillo, Luis † >> | 26 | 2019 | R | 50 | 26 | 26 | 17 | 4 | 3.46 | .294 | 1.22 | 7.4 | 3.6 | 9.3 | 158.2 | 130 | 64 | 61 | 11 | 64 | 163 | 0 | 0 | 0 | 0 | 16 | 4 | 6 | 3.13 |
| RP | Uehara, K.Uehara, Koji # >> | 38 | 2013 | R | 100 | 70 | 0 | 4 | 1 | 3.03 | .260 | 1.00 | 7.0 | 2.0 | 9.9 | 95.0 | 74 | 32 | 32 | 15 | 21 | 105 | 0 | 5 | 1 | 0 | 0 | 5 | 1 | 3.66 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 88 | 62 | 0 | 2 | 0 | 2.26 | .265 | 1.05 | 5.8 | 3.8 | 12.2 | 79.2 | 51 | 20 | 20 | 6 | 33 | 107 | 0 | 11 | 0 | 0 | 0 | 2 | 2 | 2.61 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 60 | 0 | 3 | 2 | 3.53 | .290 | 1.18 | 7.4 | 3.3 | 9.9 | 58.2 | 48 | 23 | 23 | 4 | 21 | 64 | 0 | 15 | 1 | 0 | 0 | 3 | 0 | 2.93 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 61 | 39 | 0 | 2 | 1 | 2.76 | .302 | 1.25 | 6.6 | 4.7 | 9.0 | 42.1 | 31 | 14 | 13 | 2 | 22 | 42 | 0 | 2 | 0 | 0 | 0 | 2 | 4 | 3.33 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 57 | 17 | 0 | 2 | 3 | 11.47 | .434 | 2.30 | 14.6 | 6.4 | 7.5 | 24.1 | 39 | 31 | 31 | 2 | 17 | 20 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.54 |