| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 90 | 29 | 29 | 17 | 9 | 3.14 | .293 | 1.21 | 7.9 | 3.0 | 6.8 | 212.0 | 186 | 80 | 74 | 15 | 70 | 161 | 8 | 0 | 0 | 3 | 20 | 7 | 3 | 3.49 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 28 | 28 | 11 | 12 | 4.37 | .292 | 1.22 | 8.4 | 2.6 | 8.6 | 171.0 | 159 | 84 | 83 | 22 | 49 | 164 | 0 | 0 | 0 | 0 | 12 | 4 | 4 | 3.68 |
| SP | Gooden, D.Gooden, Dwight † # >> | 21 | 1985 | R | 75 | 27 | 27 | 14 | 7 | 3.64 | .265 | 1.05 | 7.2 | 2.3 | 8.4 | 180.2 | 143 | 73 | 73 | 20 | 46 | 167 | 12 | 0 | 0 | 5 | 15 | 6 | 0 | 3.46 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 27 | 27 | 7 | 9 | 4.19 | .319 | 1.40 | 7.2 | 5.4 | 8.7 | 154.2 | 124 | 73 | 72 | 20 | 93 | 149 | 0 | 0 | 0 | 0 | 13 | 0 | 2 | 4.56 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 71 | 74 | 0 | 4 | 2 | 3.46 | .257 | 1.01 | 5.9 | 3.2 | 10.3 | 75.1 | 49 | 32 | 29 | 7 | 27 | 86 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 3.08 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 65 | 0 | 3 | 0 | 2.94 | .269 | 1.10 | 6.2 | 3.8 | 13.1 | 64.1 | 44 | 21 | 21 | 6 | 27 | 93 | 0 | 6 | 2 | 0 | 0 | 0 | 2 | 2.58 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 47 | 0 | 5 | 1 | 2.19 | .220 | 0.81 | 3.9 | 3.4 | 9.3 | 53.1 | 23 | 13 | 13 | 2 | 20 | 55 | 0 | 6 | 1 | 0 | 0 | 2 | 6 | 2.66 |
| RP | Saito, T.Saito, Takashi # >> | 37 | 2007 | R | 90 | 27 | 0 | 1 | 5 | 4.41 | .315 | 1.38 | 9.8 | 2.8 | 9.0 | 32.2 | 35 | 17 | 16 | 10 | 10 | 32 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 61 | 55 | 0 | 1 | 1 | 4.01 | .289 | 1.20 | 6.4 | 4.5 | 10.7 | 42.2 | 30 | 19 | 19 | 3 | 21 | 50 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 3.12 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 87 | 68 | 0 | 2 | 3 | 2.91 | .324 | 1.38 | 8.3 | 4.3 | 11.1 | 55.2 | 51 | 22 | 18 | 7 | 26 | 68 | 0 | 3 | 3 | 0 | 0 | 3 | 4 | 3.76 |