| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 29 | 29 | 7 | 12 | 3.95 | .290 | 1.20 | 7.0 | 3.9 | 9.5 | 186.2 | 144 | 88 | 82 | 32 | 80 | 196 | 3 | 0 | 0 | 0 | 18 | 5 | 3 | 4.50 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 28 | 28 | 11 | 10 | 3.32 | .283 | 1.18 | 7.8 | 2.9 | 6.0 | 154.1 | 133 | 66 | 57 | 17 | 49 | 102 | 1 | 0 | 0 | 1 | 11 | 1 | 4 | 4.08 |
| SP | Hunter, C.Hunter, Catfish † >> | 26 | 1972 | R | 84 | 28 | 28 | 13 | 11 | 3.59 | .283 | 1.17 | 7.6 | 3.0 | 6.5 | 205.2 | 172 | 89 | 82 | 25 | 69 | 148 | 7 | 0 | 0 | 5 | 15 | 3 | 7 | 4.20 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 28 | 28 | 10 | 9 | 4.74 | .325 | 1.43 | 9.5 | 3.5 | 7.0 | 176.2 | 185 | 96 | 93 | 29 | 68 | 137 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 4.78 |
| SP | DeLeon, J.DeLeon, Jose # >> | 29 | 1989 | R | 58 | 29 | 28 | 13 | 7 | 4.02 | .330 | 1.45 | 9.1 | 4.0 | 6.4 | 174.2 | 176 | 78 | 78 | 26 | 78 | 123 | 0 | 0 | 0 | 0 | 15 | 4 | 1 | 4.94 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 96 | 74 | 0 | 5 | 2 | 2.37 | .223 | 0.84 | 6.0 | 1.6 | 8.2 | 110.1 | 73 | 30 | 29 | 10 | 20 | 100 | 0 | 8 | 0 | 0 | 0 | 2 | 2 | 2.96 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 69 | 0 | 7 | 3 | 3.82 | .258 | 1.04 | 7.9 | 1.6 | 9.4 | 96.2 | 84 | 43 | 41 | 16 | 17 | 100 | 0 | 7 | 4 | 0 | 0 | 0 | 0 | 3.61 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 58 | 0 | 4 | 3 | 2.69 | .282 | 1.16 | 5.6 | 5.0 | 11.6 | 63.2 | 39 | 20 | 19 | 7 | 35 | 81 | 0 | 11 | 0 | 0 | 0 | 1 | 4 | 3.59 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 23 | 0 | 4 | 1 | 5.46 | .306 | 1.29 | 6.1 | 5.5 | 8.0 | 28.0 | 19 | 17 | 17 | 4 | 17 | 25 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.00 |