| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 10 | 10 | 3.96 | .300 | 1.25 | 8.6 | 2.6 | 10.6 | 220.2 | 211 | 107 | 97 | 40 | 64 | 260 | 0 | 0 | 0 | 0 | 20 | 9 | 0 | 4.00 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 85 | 33 | 33 | 15 | 14 | 5.22 | .335 | 1.48 | 10.6 | 2.7 | 6.4 | 236.0 | 279 | 137 | 137 | 32 | 71 | 168 | 10 | 0 | 0 | 1 | 13 | 6 | 5 | 4.32 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 32 | 32 | 11 | 8 | 3.56 | .322 | 1.42 | 9.2 | 3.6 | 7.6 | 202.1 | 206 | 82 | 80 | 20 | 81 | 171 | 0 | 0 | 0 | 0 | 22 | 1 | 10 | 3.81 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 31 | 31 | 8 | 17 | 6.95 | .356 | 1.63 | 12.0 | 2.7 | 6.5 | 194.1 | 258 | 150 | 150 | 42 | 59 | 140 | 2 | 0 | 0 | 0 | 9 | 5 | 3 | 5.36 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 85 | 0 | 3 | 8 | 2.34 | .266 | 1.07 | 5.8 | 3.9 | 10.7 | 119.1 | 77 | 33 | 31 | 8 | 51 | 141 | 0 | 10 | 1 | 0 | 0 | 2 | 11 | 2.84 |
| RP | Gossage, R.Gossage, Rich # >> | 30 | 1981 | R | 88 | 73 | 0 | 2 | 9 | 4.68 | .323 | 1.43 | 8.6 | 4.3 | 9.0 | 90.1 | 86 | 48 | 47 | 14 | 43 | 90 | 0 | 7 | 5 | 0 | 0 | 0 | 2 | 4.46 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 75 | 57 | 0 | 4 | 4 | 2.85 | .284 | 1.18 | 6.3 | 4.4 | 9.7 | 66.1 | 46 | 21 | 21 | 5 | 32 | 71 | 0 | 6 | 1 | 0 | 0 | 1 | 7 | 3.33 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 63 | 42 | 0 | 2 | 1 | 4.36 | .350 | 1.55 | 9.6 | 4.4 | 9.8 | 43.1 | 46 | 23 | 21 | 5 | 21 | 47 | 0 | 5 | 2 | 0 | 0 | 3 | 2 | 4.00 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 1 | 0 | 0 | 0 | 3.00 | .250 | 1.00 | 9.0 | 0.0 | 18.0 | 3.0 | 3 | 1 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |