| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 30 | 30 | 11 | 14 | 5.00 | .316 | 1.37 | 10.4 | 2.0 | 9.7 | 201.2 | 232 | 117 | 112 | 30 | 45 | 217 | 2 | 0 | 0 | 0 | 12 | 3 | 8 | 3.50 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 29 | 29 | 8 | 16 | 6.25 | .346 | 1.56 | 11.4 | 2.6 | 8.6 | 170.0 | 216 | 121 | 118 | 37 | 49 | 163 | 1 | 0 | 0 | 0 | 11 | 5 | 6 | 4.86 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 79 | 29 | 29 | 10 | 14 | 5.14 | .338 | 1.53 | 9.9 | 3.8 | 7.8 | 198.0 | 218 | 121 | 113 | 33 | 84 | 172 | 3 | 0 | 0 | 0 | 11 | 1 | 12 | 4.72 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 28 | 28 | 9 | 7 | 3.90 | .302 | 1.25 | 8.4 | 2.9 | 6.0 | 154.2 | 144 | 68 | 67 | 23 | 49 | 102 | 0 | 0 | 0 | 0 | 10 | 8 | 1 | 4.73 |
| SU | Benoit, J.Benoit, Joaquin $$ >> | 33 | 2010 | R | 94 | 58 | 0 | 5 | 0 | 2.97 | .268 | 1.09 | 7.5 | 2.4 | 8.5 | 72.2 | 60 | 24 | 24 | 8 | 19 | 68 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 3.39 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 91 | 53 | 0 | 6 | 5 | 3.21 | .285 | 1.18 | 7.6 | 3.1 | 7.4 | 56.0 | 47 | 22 | 20 | 5 | 19 | 46 | 0 | 29 | 6 | 0 | 0 | 1 | 0 | 3.59 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 67 | 0 | 4 | 4 | 3.01 | .291 | 1.21 | 7.3 | 3.6 | 7.9 | 74.2 | 60 | 27 | 25 | 7 | 30 | 65 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.77 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 75 | 26 | 0 | 0 | 1 | 6.68 | .353 | 1.64 | 13.2 | 1.7 | 7.9 | 32.1 | 47 | 24 | 24 | 4 | 6 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 27 | 0 | 0 | 1 | 6.23 | .364 | 1.71 | 12.6 | 3.0 | 10.2 | 30.1 | 42 | 21 | 21 | 5 | 10 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.90 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 21 | 0 | 3 | 3 | 5.68 | .321 | 1.40 | 10.0 | 2.7 | 8.5 | 84.0 | 93 | 54 | 53 | 19 | 25 | 79 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.99 |