| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 25 | 25 | 11 | 10 | 4.07 | .299 | 1.26 | 9.0 | 2.4 | 4.7 | 190.0 | 189 | 89 | 86 | 21 | 50 | 99 | 6 | 0 | 0 | 3 | 14 | 4 | 3 | 4.25 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 25 | 25 | 12 | 9 | 4.64 | .322 | 1.41 | 9.7 | 3.1 | 7.6 | 174.2 | 187 | 90 | 90 | 27 | 60 | 146 | 2 | 0 | 0 | 0 | 11 | 2 | 5 | 4.41 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 25 | 25 | 9 | 11 | 4.59 | .315 | 1.36 | 9.4 | 2.9 | 7.1 | 180.1 | 188 | 96 | 92 | 29 | 58 | 141 | 4 | 0 | 0 | 1 | 13 | 3 | 2 | 4.54 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 68 | 0 | 1 | 1 | 2.56 | .221 | 0.80 | 5.6 | 1.6 | 8.4 | 56.1 | 35 | 18 | 16 | 4 | 10 | 52 | 0 | 6 | 0 | 0 | 0 | 3 | 2 | 2.77 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 23 | 0 | 2 | 1 | 2.89 | .243 | 0.96 | 5.0 | 4.0 | 11.0 | 18.2 | 10 | 6 | 6 | 1 | 8 | 22 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.61 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 42 | 0 | 2 | 2 | 3.52 | .289 | 1.17 | 6.3 | 4.3 | 9.4 | 23.0 | 16 | 9 | 9 | 4 | 11 | 24 | 0 | 3 | 3 | 0 | 0 | 1 | 4 | 4.74 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 20 | 0 | 1 | 1 | 3.45 | .301 | 1.29 | 8.0 | 3.9 | 8.7 | 28.2 | 25 | 13 | 11 | 3 | 12 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 16 | 0 | 1 | 1 | 4.83 | .335 | 1.49 | 7.8 | 5.8 | 6.6 | 59.2 | 51 | 33 | 32 | 10 | 38 | 43 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.73 |