| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 29 | 29 | 10 | 14 | 3.79 | .289 | 1.20 | 8.7 | 2.2 | 8.4 | 209.0 | 201 | 96 | 88 | 28 | 50 | 194 | 6 | 0 | 0 | 1 | 18 | 4 | 5 | 3.66 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 28 | 28 | 12 | 9 | 5.22 | .335 | 1.49 | 9.7 | 3.7 | 4.7 | 176.0 | 190 | 108 | 102 | 23 | 72 | 91 | 2 | 0 | 0 | 0 | 12 | 4 | 5 | 4.96 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 68 | 27 | 27 | 11 | 8 | 4.90 | .304 | 1.29 | 8.7 | 3.0 | 8.5 | 185.1 | 179 | 104 | 101 | 33 | 61 | 175 | 4 | 0 | 0 | 1 | 10 | 3 | 1 | 4.46 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 70 | 0 | 3 | 4 | 3.90 | .331 | 1.46 | 9.2 | 4.0 | 9.4 | 87.2 | 89 | 42 | 38 | 9 | 39 | 91 | 0 | 6 | 2 | 0 | 0 | 2 | 1 | 3.67 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 65 | 0 | 2 | 6 | 3.93 | .287 | 1.18 | 8.7 | 2.0 | 8.5 | 84.2 | 81 | 39 | 37 | 14 | 19 | 79 | 0 | 9 | 5 | 0 | 0 | 2 | 3 | 4.04 |
| RP | Holland, G.Holland, Greg # >> | 27 | 2013 | R | 71 | 55 | 0 | 3 | 2 | 6.25 | .349 | 1.58 | 10.7 | 3.6 | 8.7 | 63.1 | 75 | 49 | 44 | 10 | 25 | 61 | 0 | 5 | 0 | 0 | 0 | 2 | 3 | 4.41 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 1 | 1 | 0 | 1 | 19.29 | .462 | 2.57 | 22.5 | 4.5 | 13.5 | 2.1 | 5 | 5 | 5 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.50 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 4 | 0 | 1 | 0 | 0.00 | .375 | 1.80 | 15.0 | 3.0 | 9.0 | 3.1 | 5 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 52 | 28 | 0 | 3 | 6 | 5.26 | .338 | 1.53 | 11.2 | 2.5 | 4.8 | 53.0 | 66 | 33 | 31 | 8 | 15 | 28 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.75 |