| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 29 | 29 | 13 | 8 | 2.35 | .254 | 0.98 | 6.5 | 2.4 | 6.2 | 195.1 | 141 | 55 | 51 | 12 | 51 | 135 | 3 | 0 | 0 | 0 | 22 | 7 | 4 | 3.31 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 29 | 29 | 14 | 10 | 2.86 | .258 | 1.04 | 7.5 | 1.9 | 5.2 | 208.0 | 173 | 67 | 66 | 15 | 43 | 121 | 2 | 0 | 0 | 2 | 20 | 1 | 0 | 3.41 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 28 | 28 | 14 | 6 | 3.86 | .281 | 1.17 | 8.3 | 2.2 | 4.7 | 174.2 | 161 | 79 | 75 | 24 | 43 | 91 | 2 | 0 | 0 | 1 | 16 | 1 | 3 | 4.51 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 45 | 26 | 26 | 14 | 6 | 3.75 | .285 | 1.19 | 7.4 | 3.4 | 6.5 | 160.2 | 131 | 69 | 67 | 13 | 60 | 115 | 3 | 0 | 0 | 2 | 16 | 1 | 5 | 3.76 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 73 | 0 | 5 | 3 | 2.57 | .250 | 0.99 | 5.1 | 3.9 | 10.2 | 98.0 | 55 | 28 | 28 | 10 | 42 | 111 | 0 | 8 | 3 | 0 | 0 | 1 | 2 | 3.38 |
| RP | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 87 | 61 | 0 | 8 | 4 | 2.81 | .257 | 1.04 | 7.9 | 1.4 | 7.2 | 77.0 | 68 | 25 | 24 | 6 | 12 | 62 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 2.87 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 45 | 0 | 3 | 2 | 2.12 | .267 | 1.07 | 5.7 | 4.1 | 9.8 | 46.2 | 29 | 11 | 11 | 4 | 21 | 50 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.39 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 28 | 0 | 1 | 3 | 3.34 | .270 | 1.11 | 4.7 | 5.6 | 8.4 | 29.2 | 15 | 11 | 11 | 1 | 18 | 27 | 0 | 5 | 0 | 0 | 0 | 0 | 3 | 3.45 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 9 | 0 | 0 | 0 | 4.00 | .341 | 1.50 | 9.0 | 4.5 | 8.5 | 18.0 | 18 | 11 | 8 | 1 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.50 |