| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 24 | 24 | 8 | 11 | 3.52 | .295 | 1.23 | 8.1 | 3.0 | 8.9 | 158.1 | 143 | 65 | 62 | 15 | 52 | 156 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.32 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 23 | 23 | 2 | 10 | 6.43 | .383 | 1.85 | 12.1 | 4.6 | 4.7 | 112.0 | 150 | 84 | 80 | 9 | 57 | 59 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4.57 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 23 | 23 | 5 | 8 | 5.32 | .337 | 1.52 | 10.5 | 3.2 | 8.1 | 137.0 | 160 | 82 | 81 | 21 | 48 | 124 | 0 | 0 | 0 | 0 | 7 | 1 | 4 | 4.26 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 23 | 23 | 8 | 8 | 5.70 | .352 | 1.61 | 10.1 | 4.4 | 7.7 | 128.0 | 144 | 90 | 81 | 16 | 62 | 110 | 0 | 0 | 0 | 0 | 9 | 3 | 12 | 4.43 |
| SP | Pfiester, J.Pfiester, Jack † # >> | 28 | 1906 | L | 74 | 22 | 22 | 14 | 7 | 2.74 | .253 | 1.02 | 7.0 | 2.3 | 5.0 | 180.2 | 139 | 58 | 55 | 17 | 45 | 99 | 14 | 0 | 0 | 5 | 15 | 0 | 2 | 3.88 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 58 | 0 | 5 | 2 | 3.87 | .282 | 1.15 | 6.5 | 3.9 | 9.1 | 97.2 | 70 | 43 | 42 | 13 | 42 | 98 | 0 | 4 | 5 | 0 | 0 | 3 | 0 | 4.11 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 48 | 0 | 2 | 3 | 3.43 | .301 | 1.24 | 6.3 | 5.0 | 10.4 | 60.1 | 42 | 24 | 23 | 10 | 33 | 69 | 0 | 2 | 3 | 0 | 0 | 3 | 0 | 4.67 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 4 | 0 | 0 | 1 | 9.95 | .457 | 2.53 | 18.0 | 6.0 | 10.5 | 6.1 | 12 | 7 | 7 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.83 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 24 | 0 | 1 | 5 | 6.47 | .407 | 2.03 | 12.4 | 5.9 | 4.8 | 32.0 | 44 | 25 | 23 | 2 | 21 | 17 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.81 |