| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 23 | 23 | 9 | 7 | 4.64 | .301 | 1.27 | 8.6 | 3.0 | 4.9 | 143.2 | 136 | 78 | 74 | 16 | 47 | 78 | 0 | 0 | 0 | 0 | 11 | 3 | 4 | 4.41 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 23 | 23 | 9 | 7 | 4.20 | .293 | 1.23 | 9.1 | 2.0 | 5.0 | 141.1 | 142 | 68 | 66 | 16 | 32 | 79 | 3 | 0 | 0 | 1 | 12 | 2 | 2 | 4.08 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 22 | 22 | 7 | 5 | 4.02 | .304 | 1.30 | 8.5 | 3.2 | 7.5 | 134.1 | 127 | 60 | 60 | 11 | 47 | 112 | 1 | 0 | 0 | 0 | 12 | 2 | 0 | 3.49 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 54 | 0 | 7 | 4 | 3.38 | .256 | 1.01 | 7.5 | 1.7 | 10.0 | 53.1 | 44 | 21 | 20 | 4 | 10 | 59 | 0 | 32 | 3 | 0 | 0 | 1 | 0 | 2.38 |
| SU | Gossage, R.Gossage, Rich # >> | 30 | 1981 | R | 90 | 46 | 0 | 2 | 4 | 5.93 | .349 | 1.59 | 8.3 | 5.9 | 7.9 | 41.0 | 38 | 27 | 27 | 3 | 27 | 36 | 0 | 2 | 8 | 0 | 0 | 1 | 4 | 4.24 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 51 | 0 | 2 | 6 | 3.22 | .290 | 1.23 | 7.3 | 3.8 | 5.5 | 64.1 | 52 | 29 | 23 | 10 | 27 | 39 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 5.08 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 44 | 0 | 2 | 4 | 3.65 | .249 | 0.99 | 7.0 | 2.0 | 8.4 | 44.1 | 34 | 18 | 18 | 12 | 10 | 41 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 5.36 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 18 | 0 | 3 | 1 | 3.32 | .293 | 1.22 | 7.7 | 3.3 | 5.2 | 81.1 | 69 | 35 | 30 | 7 | 30 | 47 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4.15 |