| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 24 | 24 | 11 | 12 | 3.22 | .294 | 1.22 | 8.0 | 3.0 | 7.0 | 178.2 | 158 | 75 | 64 | 12 | 60 | 138 | 9 | 0 | 0 | 2 | 15 | 5 | 1 | 3.42 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 23 | 23 | 5 | 8 | 4.61 | .315 | 1.35 | 9.6 | 2.5 | 5.1 | 152.1 | 162 | 84 | 78 | 15 | 43 | 86 | 2 | 0 | 0 | 0 | 10 | 5 | 2 | 4.10 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 23 | 23 | 9 | 11 | 4.03 | .279 | 1.16 | 8.7 | 1.7 | 5.1 | 172.0 | 167 | 84 | 77 | 21 | 33 | 98 | 11 | 0 | 0 | 1 | 13 | 0 | 0 | 4.02 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 58 | 0 | 5 | 1 | 3.57 | .281 | 1.17 | 7.4 | 3.1 | 9.5 | 58.0 | 48 | 23 | 23 | 6 | 20 | 61 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.28 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 39 | 0 | 0 | 5 | 6.05 | .356 | 1.63 | 9.9 | 5.0 | 8.3 | 38.2 | 42 | 26 | 26 | 5 | 21 | 35 | 0 | 1 | 9 | 0 | 0 | 1 | 0 | 4.61 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 42 | 0 | 3 | 6 | 2.90 | .240 | 0.93 | 6.4 | 2.0 | 9.2 | 49.2 | 35 | 16 | 16 | 3 | 11 | 50 | 0 | 18 | 3 | 0 | 0 | 1 | 1 | 2.49 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 34 | 0 | 1 | 3 | 5.09 | .299 | 1.28 | 9.7 | 2.0 | 6.3 | 40.2 | 43 | 25 | 23 | 10 | 9 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.53 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 25 | 0 | 2 | 0 | 6.43 | .359 | 1.64 | 9.6 | 5.1 | 8.4 | 28.0 | 30 | 20 | 20 | 3 | 16 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.36 |