| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 80 | 23 | 23 | 8 | 10 | 5.13 | .303 | 1.27 | 8.7 | 2.7 | 9.6 | 131.2 | 127 | 78 | 75 | 22 | 40 | 140 | 2 | 0 | 0 | 1 | 11 | 5 | 3 | 4.08 |
| SP | Halladay, R.Halladay, Roy † >> | 28 | 2005 | R | 87 | 22 | 22 | 11 | 8 | 3.16 | .270 | 1.08 | 7.6 | 2.2 | 5.2 | 159.2 | 135 | 64 | 56 | 14 | 38 | 92 | 8 | 0 | 0 | 1 | 16 | 4 | 3 | 3.78 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 76 | 22 | 21 | 9 | 4 | 3.69 | .313 | 1.33 | 8.2 | 3.8 | 9.1 | 126.2 | 115 | 54 | 52 | 17 | 53 | 128 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 4.10 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 22 | 21 | 8 | 5 | 6.34 | .350 | 1.60 | 10.4 | 4.0 | 5.5 | 116.1 | 134 | 84 | 82 | 21 | 52 | 71 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 5.53 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 48 | 0 | 6 | 3 | 3.38 | .259 | 1.03 | 7.0 | 2.3 | 11.0 | 50.2 | 39 | 19 | 19 | 3 | 13 | 61 | 0 | 28 | 4 | 0 | 0 | 1 | 0 | 2.18 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 44 | 0 | 5 | 1 | 2.59 | .272 | 1.10 | 6.3 | 3.7 | 7.6 | 59.0 | 41 | 18 | 17 | 5 | 24 | 50 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.68 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 29 | 0 | 4 | 0 | 4.86 | .346 | 1.56 | 11.7 | 2.5 | 10.6 | 33.1 | 43 | 20 | 18 | 9 | 9 | 39 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.09 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 23 | 0 | 0 | 0 | 1.52 | .220 | 0.80 | 5.5 | 2.0 | 13.7 | 23.2 | 14 | 4 | 4 | 4 | 5 | 35 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.00 |