| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 16 | 16 | 8 | 3 | 3.49 | .268 | 1.05 | 7.5 | 2.0 | 7.1 | 111.0 | 92 | 44 | 43 | 14 | 25 | 88 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 3.86 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 16 | 16 | 4 | 9 | 6.53 | .329 | 1.45 | 10.1 | 3.1 | 7.5 | 93.2 | 104 | 77 | 68 | 16 | 32 | 77 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.68 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 24 | 2005 | R | 69 | 15 | 15 | 7 | 4 | 5.03 | .352 | 1.60 | 9.9 | 4.5 | 5.9 | 91.1 | 100 | 53 | 51 | 9 | 46 | 60 | 1 | 0 | 0 | 0 | 4 | 3 | 1 | 4.58 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 43 | 0 | 2 | 2 | 2.81 | .288 | 1.18 | 8.2 | 2.5 | 9.9 | 57.2 | 52 | 18 | 18 | 7 | 16 | 63 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.33 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 39 | 0 | 2 | 2 | 6.29 | .345 | 1.56 | 9.6 | 4.7 | 9.6 | 48.2 | 51 | 35 | 34 | 9 | 25 | 51 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.94 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 31 | 0 | 2 | 2 | 6.40 | .370 | 1.76 | 10.1 | 5.9 | 10.1 | 32.1 | 36 | 23 | 23 | 4 | 21 | 36 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.34 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 24 | 0 | 2 | 2 | 3.25 | .278 | 1.16 | 8.0 | 2.7 | 6.0 | 27.2 | 24 | 10 | 10 | 3 | 8 | 18 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 56 | 23 | 0 | 2 | 0 | 1.93 | .205 | 0.77 | 3.5 | 3.5 | 10.2 | 23.1 | 9 | 5 | 5 | 2 | 9 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.04 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 17 | 0 | 1 | 1 | 4.98 | .316 | 1.34 | 8.1 | 4.3 | 9.9 | 21.2 | 19 | 12 | 12 | 4 | 10 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.86 |