| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 27 | 27 | 11 | 11 | 4.07 | .304 | 1.26 | 7.9 | 3.5 | 8.7 | 179.1 | 157 | 89 | 81 | 23 | 69 | 174 | 1 | 0 | 0 | 0 | 16 | 9 | 5 | 4.03 |
| SP | Severino, L.Severino, Luis >> | 23 | 2017 | R | 74 | 27 | 27 | 6 | 11 | 5.30 | .316 | 1.38 | 9.2 | 3.3 | 9.4 | 161.1 | 164 | 95 | 95 | 27 | 59 | 169 | 0 | 0 | 0 | 0 | 9 | 1 | 2 | 4.20 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 58 | 26 | 26 | 10 | 9 | 4.10 | .316 | 1.34 | 8.1 | 4.0 | 7.6 | 178.0 | 160 | 82 | 81 | 16 | 79 | 151 | 1 | 0 | 0 | 1 | 15 | 8 | 1 | 3.94 |
| SP | Wood, A.Wood, Alex † # >> | 26 | 2017 | L | 56 | 26 | 26 | 15 | 5 | 4.48 | .293 | 1.21 | 8.3 | 2.6 | 7.9 | 150.2 | 139 | 75 | 75 | 22 | 44 | 132 | 0 | 0 | 0 | 0 | 16 | 4 | 1 | 4.11 |
| SP | Jimenez, U.Jimenez, Ubaldo # | 26 | 2010 | R | 43 | 25 | 25 | 10 | 10 | 5.25 | .351 | 1.57 | 9.0 | 5.2 | 7.7 | 157.2 | 157 | 101 | 92 | 24 | 91 | 134 | 1 | 0 | 0 | 0 | 14 | 8 | 6 | 5.17 |
| RP | Green, C.Green, Chad † >> | 26 | 2017 | R | 97 | 75 | 0 | 6 | 5 | 2.75 | .261 | 1.02 | 6.4 | 2.8 | 10.2 | 134.1 | 95 | 44 | 41 | 12 | 42 | 152 | 0 | 8 | 5 | 0 | 0 | 5 | 3 | 2.95 |
| RP | Salas, F.Salas, Fernando >> | 26 | 2011 | R | 44 | 40 | 0 | 2 | 3 | 3.17 | .253 | 0.95 | 6.8 | 1.9 | 8.3 | 48.1 | 36 | 17 | 17 | 7 | 10 | 44 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 3.88 |
| SP | Mikolas, M.Mikolas, Miles >> | 29 | 2018 | R | 33 | 1 | 0 | 0 | 0 | 54.00 | .667 | 6.00 | - | - | - | 0.2 | 3 | 4 | 4 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Archer, C.Archer, Chris >> | 26 | 2015 | R | 42 | 20 | 0 | 2 | 2 | 5.32 | .333 | 1.45 | 11.0 | 2.0 | 11.5 | 22.0 | 27 | 14 | 13 | 3 | 5 | 28 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.05 |