| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 95 | 32 | 32 | 14 | 12 | 4.10 | .313 | 1.35 | 8.1 | 4.1 | 8.6 | 173.1 | 155 | 87 | 79 | 23 | 79 | 165 | 1 | 0 | 0 | 1 | 8 | 3 | 4 | 4.24 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 32 | 32 | 11 | 13 | 4.70 | .333 | 1.46 | 9.4 | 3.8 | 5.7 | 193.1 | 202 | 106 | 101 | 18 | 81 | 122 | 5 | 0 | 0 | 0 | 12 | 7 | 3 | 4.32 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 33 | 29 | 7 | 11 | 4.99 | .302 | 1.28 | 8.5 | 3.0 | 4.3 | 167.2 | 158 | 94 | 93 | 22 | 56 | 79 | 7 | 2 | 0 | 2 | 12 | 4 | 6 | 4.84 |
| CL | Eckersley, D.Eckersley, Dennis $$ >> | 36 | 1990 | R | 88 | 55 | 0 | 1 | 6 | 4.19 | .271 | 1.12 | 8.0 | 2.2 | 8.0 | 53.2 | 47 | 27 | 25 | 6 | 13 | 47 | 0 | 31 | 6 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Brewer, J.Brewer, Jim # >> | 35 | 1972 | L | 73 | 92 | 0 | 7 | 5 | 4.32 | .288 | 1.21 | 7.7 | 3.2 | 5.6 | 110.1 | 94 | 58 | 53 | 16 | 39 | 69 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 84 | 0 | 4 | 3 | 2.07 | .311 | 1.33 | 6.7 | 5.4 | 8.2 | 82.2 | 61 | 23 | 19 | 4 | 49 | 75 | 0 | 2 | 0 | 0 | 0 | 2 | 5 | 3.67 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 86 | 65 | 0 | 6 | 2 | 3.36 | .297 | 1.22 | 8.1 | 3.0 | 10.1 | 67.0 | 60 | 26 | 25 | 6 | 22 | 75 | 0 | 2 | 4 | 0 | 0 | 3 | 3 | 3.04 |
| SU | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 56 | 0 | 4 | 4 | 3.71 | .290 | 1.21 | 8.5 | 2.4 | 7.8 | 70.1 | 66 | 30 | 29 | 10 | 19 | 61 | 0 | 0 | 8 | 0 | 0 | 1 | 3 | 3.97 |