| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 5 | 5 | 1 | 2 | 3.31 | .221 | 0.82 | 4.6 | 2.8 | 11.3 | 35.1 | 18 | 14 | 13 | 7 | 11 | 44 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.11 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 5 | 5 | 3 | 2 | 5.91 | .373 | 1.75 | 12.7 | 3.1 | 9.6 | 32.0 | 45 | 26 | 21 | 7 | 11 | 34 | 1 | 0 | 0 | 0 | 1 | 1 | 2 | 4.84 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 5 | 5 | 2 | 2 | 5.20 | .359 | 1.68 | 12.3 | 3.0 | 6.8 | 36.1 | 49 | 27 | 21 | 9 | 12 | 27 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.75 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 4 | 4 | 0 | 3 | 5.40 | .370 | 1.76 | 11.5 | 4.3 | 6.5 | 25.0 | 32 | 19 | 15 | 4 | 12 | 18 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 5.08 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 13 | 0 | 0 | 1 | 3.00 | .308 | 1.27 | 7.2 | 4.2 | 13.2 | 15.0 | 12 | 6 | 5 | 0 | 7 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 1.67 |
| RP | Eckersley, D.Eckersley, Dennis $ >> | 36 | 1990 | R | 87 | 12 | 0 | 0 | 0 | 1.29 | .311 | 1.36 | 10.9 | 1.3 | 10.9 | 14.0 | 17 | 2 | 2 | 0 | 2 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 7 | 0 | 2 | 1 | 1.17 | .179 | 0.65 | 3.9 | 2.6 | 5.1 | 7.2 | 3 | 1 | 1 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.71 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 3 | 0 | 0 | 0 | 15.43 | .364 | 1.71 | 9.0 | 9.0 | 13.5 | 2.1 | 2 | 4 | 4 | 0 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 |