| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 8 | 13 | 5.01 | .326 | 1.43 | 10.2 | 2.7 | 9.2 | 233.1 | 264 | 136 | 130 | 30 | 70 | 237 | 2 | 0 | 0 | 1 | 9 | 4 | 6 | 3.59 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 33 | 33 | 12 | 14 | 4.67 | .294 | 1.24 | 9.1 | 2.0 | 4.2 | 181.1 | 183 | 95 | 94 | 26 | 41 | 84 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 4.67 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 32 | 32 | 7 | 18 | 5.55 | .332 | 1.47 | 10.6 | 2.7 | 8.4 | 212.1 | 249 | 142 | 131 | 27 | 64 | 199 | 1 | 0 | 0 | 0 | 13 | 4 | 9 | 3.74 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 91 | 0 | 6 | 2 | 4.33 | .318 | 1.39 | 7.6 | 4.9 | 9.1 | 124.2 | 105 | 66 | 60 | 14 | 68 | 125 | 0 | 3 | 3 | 0 | 0 | 1 | 11 | 4.12 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 61 | 0 | 3 | 5 | 3.29 | .368 | 1.73 | 7.1 | 8.4 | 7.7 | 63.0 | 50 | 27 | 23 | 9 | 59 | 54 | 0 | 8 | 5 | 0 | 0 | 1 | 1 | 6.00 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 51 | 0 | 2 | 3 | 4.08 | .321 | 1.36 | 7.1 | 5.1 | 9.2 | 53.0 | 42 | 27 | 24 | 7 | 30 | 54 | 0 | 6 | 5 | 0 | 0 | 3 | 2 | 4.55 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 45 | 0 | 7 | 2 | 3.10 | .299 | 1.24 | 7.2 | 4.0 | 5.2 | 81.1 | 65 | 34 | 28 | 6 | 36 | 47 | 0 | 4 | 0 | 0 | 0 | 3 | 3 | 4.25 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 11 | 1 | 3 | 3 | 7.58 | .387 | 1.89 | 12.3 | 4.7 | 6.2 | 19.0 | 26 | 17 | 16 | 4 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.95 |