| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 36 | 36 | 17 | 9 | 3.48 | .271 | 1.09 | 7.3 | 2.5 | 8.4 | 230.1 | 187 | 91 | 89 | 25 | 63 | 215 | 0 | 0 | 0 | 0 | 26 | 7 | 0 | 3.46 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 34 | 34 | 9 | 11 | 5.18 | .330 | 1.45 | 10.0 | 3.1 | 8.9 | 182.1 | 203 | 112 | 105 | 30 | 62 | 179 | 1 | 0 | 0 | 0 | 17 | 5 | 1 | 4.28 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 33 | 33 | 8 | 11 | 5.86 | .349 | 1.59 | 10.2 | 4.2 | 7.6 | 181.1 | 205 | 126 | 118 | 26 | 84 | 153 | 1 | 0 | 0 | 1 | 12 | 2 | 1 | 4.60 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 34 | 31 | 8 | 8 | 5.18 | .335 | 1.50 | 10.7 | 2.8 | 5.2 | 191.0 | 227 | 122 | 110 | 30 | 59 | 111 | 6 | 0 | 0 | 2 | 12 | 3 | 3 | 4.85 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 97 | 0 | 7 | 5 | 4.20 | .325 | 1.43 | 8.8 | 4.1 | 8.7 | 113.2 | 110 | 59 | 53 | 18 | 52 | 109 | 0 | 1 | 7 | 0 | 0 | 2 | 0 | 4.58 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 89 | 0 | 5 | 5 | 4.48 | .329 | 1.44 | 7.3 | 5.7 | 9.0 | 96.1 | 78 | 49 | 48 | 11 | 61 | 96 | 0 | 3 | 2 | 0 | 0 | 3 | 5 | 4.49 |