| SP | Snell, B.Snell, Blake † # $ >> | 25 | 2018 | L | 80 | 35 | 35 | 19 | 8 | 3.79 | .262 | 1.05 | 6.7 | 2.8 | 7.1 | 228.0 | 169 | 96 | 96 | 30 | 70 | 181 | 2 | 0 | 0 | 1 | 21 | 4 | 6 | 4.10 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 36 | 36 | 15 | 16 | 3.06 | .269 | 1.09 | 6.7 | 3.1 | 7.4 | 267.2 | 199 | 96 | 91 | 26 | 92 | 219 | 7 | 0 | 0 | 3 | 24 | 5 | 8 | 3.72 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 73 | 34 | 34 | 16 | 6 | 3.30 | .305 | 1.28 | 6.7 | 4.9 | 7.8 | 226.1 | 168 | 85 | 83 | 18 | 122 | 197 | 0 | 0 | 0 | 0 | 20 | 8 | 11 | 4.02 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 35 | 35 | 15 | 13 | 4.14 | .295 | 1.23 | 8.5 | 2.5 | 5.9 | 254.1 | 241 | 121 | 117 | 28 | 71 | 167 | 10 | 0 | 0 | 2 | 22 | 7 | 3 | 4.04 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 96 | 0 | 6 | 1 | 3.07 | .226 | 0.88 | 5.5 | 2.4 | 7.9 | 82.0 | 50 | 29 | 28 | 10 | 22 | 72 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 3.63 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 53 | 0 | 3 | 3 | 3.27 | .266 | 1.06 | 6.6 | 3.1 | 5.9 | 41.1 | 30 | 15 | 15 | 5 | 14 | 27 | 0 | 7 | 1 | 0 | 0 | 1 | 1 | 4.37 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 71 | 0 | 3 | 2 | 2.44 | .255 | 1.01 | 5.5 | 3.7 | 10.1 | 51.2 | 31 | 14 | 14 | 4 | 21 | 57 | 0 | 10 | 3 | 0 | 0 | 1 | 0 | 3.08 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 47 | 0 | 2 | 2 | 3.40 | .312 | 1.34 | 7.8 | 4.4 | 7.6 | 39.2 | 34 | 17 | 15 | 2 | 19 | 33 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.51 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 24 | 5 | 3 | 8 | 3.70 | .283 | 1.15 | 7.4 | 3.1 | 8.5 | 82.2 | 67 | 35 | 34 | 11 | 28 | 77 | 2 | 4 | 1 | 0 | 3 | 3 | 2 | 4.00 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 28 | 24 | 11 | 8 | 3.53 | .295 | 1.25 | 6.8 | 4.5 | 8.0 | 173.1 | 130 | 75 | 68 | 20 | 86 | 153 | 2 | 0 | 0 | 0 | 16 | 2 | 2 | 4.26 |