| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 24 | 24 | 8 | 9 | 3.85 | .283 | 1.16 | 8.0 | 2.5 | 10.3 | 135.2 | 120 | 63 | 58 | 19 | 38 | 154 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.46 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 24 | 24 | 8 | 9 | 5.57 | .335 | 1.48 | 10.2 | 3.2 | 9.0 | 124.1 | 140 | 81 | 77 | 15 | 44 | 124 | 1 | 0 | 0 | 0 | 11 | 4 | 2 | 3.73 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 83 | 22 | 22 | 9 | 7 | 3.37 | .288 | 1.21 | 8.4 | 2.5 | 8.5 | 144.1 | 134 | 60 | 54 | 20 | 40 | 136 | 1 | 0 | 0 | 0 | 16 | 1 | 1 | 3.77 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 24 | 22 | 6 | 7 | 4.06 | .298 | 1.26 | 8.7 | 2.7 | 5.9 | 146.1 | 141 | 69 | 66 | 17 | 43 | 95 | 2 | 1 | 0 | 0 | 12 | 2 | 2 | 4.14 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 65 | 0 | 4 | 6 | 4.60 | .312 | 1.32 | 6.8 | 5.2 | 9.2 | 76.1 | 57 | 39 | 39 | 6 | 44 | 78 | 0 | 26 | 8 | 0 | 0 | 3 | 0 | 3.83 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 65 | 0 | 3 | 2 | 4.37 | .311 | 1.33 | 7.8 | 4.3 | 6.6 | 80.1 | 69 | 42 | 39 | 10 | 38 | 59 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 4.65 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 54 | 0 | 1 | 2 | 5.10 | .353 | 1.57 | 11.1 | 3.0 | 9.0 | 60.0 | 74 | 35 | 34 | 7 | 20 | 60 | 0 | 3 | 2 | 0 | 0 | 4 | 0 | 3.72 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 45 | 0 | 7 | 2 | 3.20 | .279 | 1.14 | 8.2 | 2.3 | 9.8 | 64.2 | 58 | 23 | 23 | 6 | 16 | 70 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.83 |