| SP | Scherzer, M.Scherzer, Max † >> | 29 | 2013 | R | 96 | 35 | 35 | 20 | 7 | 3.03 | .258 | 1.02 | 6.7 | 2.4 | 8.3 | 255.1 | 191 | 95 | 86 | 28 | 69 | 234 | 3 | 0 | 0 | 2 | 26 | 7 | 8 | 3.49 |
| SP | Kershaw, C.Kershaw, Clayton >> | 32 | 2020 | L | 100 | 35 | 35 | 13 | 12 | 3.98 | .266 | 1.06 | 7.3 | 2.3 | 8.6 | 219.1 | 178 | 98 | 97 | 26 | 55 | 210 | 1 | 0 | 0 | 1 | 21 | 6 | 0 | 3.46 |
| SP | Sanchez, A.Sanchez, Anibal >> | 29 | 2013 | R | 79 | 33 | 33 | 15 | 9 | 4.17 | .302 | 1.25 | 7.9 | 3.4 | 8.8 | 211.1 | 185 | 105 | 98 | 26 | 79 | 207 | 0 | 0 | 0 | 0 | 16 | 10 | 0 | 3.91 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 65 | 19 | 0 | 3 | 2 | 3.71 | .275 | 1.10 | 7.7 | 2.3 | 9.1 | 89.2 | 76 | 37 | 37 | 13 | 23 | 90 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.75 |
| RP | Uehara, K.Uehara, Koji >> | 36 | 2011 | R | 100 | 90 | 0 | 4 | 0 | 1.37 | .216 | 0.79 | 5.4 | 1.8 | 9.1 | 111.1 | 66 | 19 | 17 | 7 | 22 | 112 | 0 | 3 | 1 | 0 | 0 | 4 | 0 | 2.50 |
| RP | Foulke, K.Foulke, Keith † >> | 32 | 2004 | R | 91 | 68 | 0 | 6 | 11 | 3.03 | .288 | 1.20 | 7.2 | 3.6 | 6.8 | 77.1 | 62 | 29 | 26 | 7 | 31 | 58 | 0 | 27 | 5 | 0 | 0 | 1 | 3 | 3.92 |
| RP | Montgomery, M.Montgomery, Mike >> | 26 | 2016 | L | 71 | 31 | 0 | 4 | 4 | 3.89 | .310 | 1.35 | 7.8 | 4.4 | 6.2 | 39.1 | 34 | 22 | 17 | 4 | 19 | 27 | 0 | 1 | 2 | 0 | 0 | 0 | 6 | 4.41 |
| RP | Embree, A.Embree, Alan >> | 34 | 2004 | L | 64 | 16 | 0 | 4 | 1 | 3.55 | .224 | 0.87 | 6.0 | 2.3 | 8.3 | 12.2 | 8 | 6 | 5 | 1 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Remlinger, M.Remlinger, Mike >> | 37 | 2003 | L | 58 | 20 | 0 | 0 | 0 | 1.66 | .261 | 1.06 | 4.7 | 5.1 | 10.7 | 21.2 | 11 | 4 | 4 | 2 | 12 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.57 |