| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 16 | 11 | 3.75 | .293 | 1.23 | 9.1 | 2.0 | 7.7 | 235.0 | 237 | 101 | 98 | 30 | 53 | 201 | 4 | 0 | 0 | 3 | 19 | 2 | 2 | 3.65 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 32 | 32 | 9 | 8 | 3.50 | .313 | 1.36 | 7.8 | 4.4 | 8.9 | 203.0 | 177 | 83 | 79 | 21 | 100 | 200 | 0 | 0 | 0 | 0 | 19 | 1 | 4 | 3.87 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 31 | 31 | 7 | 18 | 5.08 | .317 | 1.37 | 9.1 | 3.2 | 8.5 | 200.1 | 202 | 121 | 113 | 34 | 72 | 188 | 4 | 0 | 0 | 1 | 11 | 5 | 9 | 4.49 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 30 | 30 | 14 | 14 | 4.24 | .315 | 1.36 | 9.0 | 3.2 | 4.5 | 204.0 | 205 | 109 | 96 | 24 | 73 | 103 | 9 | 0 | 0 | 2 | 15 | 3 | 1 | 4.64 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 60 | 0 | 5 | 8 | 3.20 | .292 | 1.20 | 7.6 | 3.2 | 8.8 | 59.0 | 50 | 24 | 21 | 6 | 21 | 58 | 0 | 35 | 2 | 0 | 0 | 2 | 0 | 3.53 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 44 | 0 | 2 | 3 | 6.09 | .376 | 1.80 | 9.6 | 6.8 | 6.5 | 44.1 | 47 | 31 | 30 | 8 | 33 | 32 | 0 | 2 | 4 | 0 | 0 | 0 | 4 | 6.16 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 71 | 0 | 6 | 1 | 2.36 | .250 | 0.98 | 5.1 | 3.7 | 8.8 | 80.0 | 45 | 23 | 21 | 6 | 33 | 78 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.34 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 44 | 0 | 4 | 3 | 4.06 | .335 | 1.49 | 8.0 | 5.5 | 9.2 | 44.1 | 39 | 23 | 20 | 6 | 27 | 45 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.64 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 28 | 0 | 0 | 2 | 8.06 | .369 | 1.75 | 12.2 | 4.0 | 7.2 | 25.2 | 34 | 24 | 23 | 3 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.28 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 21 | 1 | 3 | 2 | 4.76 | .315 | 1.36 | 9.6 | 2.7 | 4.9 | 92.2 | 98 | 51 | 49 | 14 | 28 | 50 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 4.87 |