| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 10 | 7 | 4.35 | .319 | 1.39 | 9.6 | 3.0 | 9.7 | 186.1 | 198 | 105 | 90 | 22 | 61 | 200 | 1 | 0 | 0 | 0 | 16 | 3 | 0 | 3.42 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 31 | 31 | 13 | 11 | 5.82 | .362 | 1.67 | 11.2 | 3.9 | 9.9 | 165.1 | 205 | 110 | 107 | 26 | 71 | 182 | 1 | 0 | 0 | 0 | 13 | 5 | 2 | 4.22 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 32 | 32 | 8 | 12 | 6.98 | .378 | 1.79 | 11.4 | 4.8 | 5.0 | 153.1 | 194 | 131 | 119 | 29 | 81 | 85 | 1 | 0 | 0 | 0 | 9 | 4 | 8 | 6.02 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 31 | 31 | 18 | 10 | 3.81 | .299 | 1.26 | 8.6 | 2.7 | 6.4 | 207.2 | 198 | 93 | 88 | 18 | 63 | 147 | 7 | 0 | 0 | 2 | 18 | 5 | 3 | 3.70 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 71 | 0 | 6 | 4 | 5.14 | .367 | 1.70 | 11.6 | 3.7 | 7.4 | 68.1 | 88 | 42 | 39 | 7 | 28 | 56 | 0 | 33 | 3 | 0 | 0 | 3 | 1 | 4.06 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 79 | 0 | 2 | 5 | 7.24 | .371 | 1.72 | 10.5 | 4.9 | 9.0 | 82.0 | 96 | 74 | 66 | 17 | 45 | 82 | 0 | 4 | 6 | 0 | 0 | 4 | 0 | 5.49 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 77 | 0 | 5 | 1 | 4.12 | .320 | 1.40 | 7.6 | 5.0 | 8.3 | 83.0 | 70 | 42 | 38 | 12 | 46 | 77 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 4.72 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 64 | 0 | 4 | 1 | 4.40 | .324 | 1.40 | 7.0 | 5.7 | 9.4 | 71.2 | 55 | 38 | 35 | 6 | 45 | 74 | 0 | 2 | 0 | 0 | 0 | 3 | 6 | 4.04 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 56 | 0 | 5 | 3 | 4.39 | .326 | 1.45 | 8.8 | 4.3 | 5.6 | 96.1 | 94 | 52 | 47 | 10 | 46 | 60 | 0 | 2 | 1 | 0 | 0 | 0 | 6 | 4.54 |