| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 31 | 30 | 16 | 6 | 3.34 | .267 | 1.08 | 7.7 | 2.1 | 5.2 | 237.1 | 202 | 90 | 88 | 24 | 54 | 137 | 11 | 0 | 0 | 2 | 20 | 3 | 3 | 3.88 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 31 | 31 | 7 | 17 | 4.25 | .304 | 1.29 | 8.6 | 3.1 | 4.8 | 224.1 | 213 | 113 | 106 | 23 | 76 | 119 | 9 | 0 | 0 | 1 | 15 | 5 | 7 | 4.36 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 31 | 31 | 12 | 11 | 4.48 | .290 | 1.20 | 7.4 | 3.4 | 8.0 | 188.2 | 155 | 97 | 94 | 21 | 72 | 168 | 0 | 0 | 0 | 0 | 20 | 4 | 3 | 3.88 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 29 | 27 | 11 | 10 | 3.12 | .282 | 1.15 | 6.8 | 3.6 | 7.0 | 190.1 | 143 | 67 | 66 | 15 | 76 | 147 | 2 | 0 | 0 | 0 | 22 | 5 | 2 | 3.76 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 89 | 0 | 4 | 5 | 3.43 | .265 | 1.06 | 7.0 | 2.6 | 8.6 | 81.1 | 63 | 33 | 31 | 6 | 23 | 77 | 0 | 9 | 3 | 0 | 0 | 2 | 4 | 2.99 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 60 | 0 | 3 | 1 | 2.36 | .265 | 1.03 | 5.5 | 3.8 | 5.9 | 61.0 | 37 | 18 | 16 | 4 | 26 | 40 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 3.97 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 37 | 0 | 5 | 3 | 3.18 | .284 | 1.17 | 5.6 | 5.0 | 7.8 | 45.1 | 28 | 16 | 16 | 1 | 25 | 39 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.29 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 32 | 0 | 3 | 3 | 3.83 | .309 | 1.34 | 7.6 | 4.7 | 5.3 | 44.2 | 37 | 19 | 19 | 4 | 23 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.57 |