| SP | Mussina, M.Mussina, Mike >> | 27 | 1995 | R | 97 | 31 | 31 | 12 | 14 | 4.13 | .304 | 1.30 | 9.0 | 2.7 | 4.9 | 217.2 | 217 | 112 | 100 | 19 | 65 | 117 | 8 | 0 | 0 | 2 | 16 | 3 | 4 | 4.00 |
| SP | Appier, K.Appier, Kevin >> | 30 | 1997 | R | 83 | 32 | 32 | 13 | 15 | 4.52 | .298 | 1.25 | 8.3 | 2.9 | 6.3 | 217.0 | 201 | 115 | 109 | 19 | 71 | 151 | 8 | 0 | 0 | 2 | 16 | 4 | 18 | 3.78 |
| SP | Mulholland, T.Mulholland, Terry # >> | 29 | 1992 | L | 73 | 30 | 30 | 14 | 8 | 4.09 | .302 | 1.28 | 9.3 | 2.3 | 5.4 | 213.2 | 220 | 99 | 97 | 10 | 54 | 127 | 3 | 0 | 0 | 2 | 17 | 3 | 4 | 3.22 |
| SP | Wilson, E.Wilson, Earl >> | 31 | 1965 | R | 63 | 29 | 29 | 12 | 9 | 3.88 | .301 | 1.28 | 8.4 | 3.1 | 4.5 | 169.1 | 157 | 82 | 73 | 7 | 59 | 85 | 0 | 0 | 0 | 0 | 14 | 3 | 4 | 3.63 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 99 | 55 | 0 | 1 | 5 | 2.07 | .234 | 0.92 | 4.9 | 3.4 | 9.3 | 61.0 | 33 | 14 | 14 | 6 | 23 | 63 | 0 | 35 | 3 | 0 | 0 | 0 | 0 | 3.34 |
| RP | Orosco, J.Orosco, Jesse >> | 40 | 1997 | L | 80 | 66 | 0 | 3 | 1 | 1.63 | .237 | 0.93 | 5.0 | 3.4 | 6.1 | 77.1 | 43 | 14 | 14 | 4 | 29 | 52 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.45 |