| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 13 | 13 | 4 | 6 | 4.70 | .343 | 1.57 | 10.0 | 4.2 | 8.0 | 84.1 | 93 | 47 | 44 | 17 | 39 | 75 | 1 | 0 | 0 | 0 | 7 | 0 | 1 | 5.24 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 13 | 13 | 3 | 7 | 5.74 | .345 | 1.56 | 10.8 | 3.3 | 4.8 | 95.2 | 114 | 64 | 61 | 13 | 35 | 51 | 2 | 0 | 0 | 0 | 4 | 2 | 1 | 4.87 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 13 | 13 | 5 | 1 | 4.64 | .326 | 1.44 | 8.7 | 4.3 | 4.7 | 85.1 | 82 | 45 | 44 | 9 | 41 | 44 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.82 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 13 | 13 | 5 | 4 | 3.84 | .323 | 1.40 | 8.9 | 3.8 | 5.4 | 91.1 | 90 | 39 | 39 | 9 | 38 | 55 | 1 | 0 | 0 | 0 | 9 | 3 | 0 | 4.43 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 13 | 13 | 6 | 4 | 4.55 | .332 | 1.48 | 9.3 | 4.0 | 5.2 | 85.0 | 88 | 48 | 43 | 12 | 38 | 49 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 5.06 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 34 | 0 | 1 | 2 | 4.23 | .276 | 1.14 | 6.3 | 4.1 | 7.8 | 44.2 | 31 | 23 | 21 | 1 | 20 | 38 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 2.93 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 30 | 0 | 2 | 4 | 5.94 | .324 | 1.44 | 7.4 | 5.7 | 10.1 | 33.1 | 27 | 23 | 22 | 6 | 21 | 37 | 0 | 4 | 4 | 0 | 0 | 0 | 6 | 5.03 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 14 | 0 | 1 | 1 | 4.70 | .361 | 1.70 | 10.8 | 4.8 | 9.6 | 15.1 | 18 | 8 | 8 | 2 | 8 | 16 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.20 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 4 | 0 | 1 | 1 | 4.26 | .345 | 1.58 | 7.5 | 7.5 | 3.0 | 6.1 | 5 | 3 | 3 | 0 | 5 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.83 |