| SP | Johnson, W.Johnson, Walter # >> | 26 | 1913 | R | 95 | 14 | 14 | 4 | 8 | 4.43 | .315 | 1.37 | 9.7 | 2.7 | 5.3 | 103.2 | 111 | 56 | 51 | 9 | 31 | 61 | 2 | 0 | 0 | 0 | 9 | 1 | 2 | 3.88 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 14 | 14 | 5 | 9 | 7.18 | .373 | 1.79 | 11.9 | 4.2 | 5.2 | 104.0 | 137 | 86 | 83 | 20 | 49 | 60 | 3 | 0 | 0 | 0 | 2 | 0 | 4 | 5.76 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 14 | 14 | 5 | 6 | 5.47 | .331 | 1.47 | 10.1 | 3.2 | 3.6 | 105.1 | 118 | 65 | 64 | 12 | 37 | 42 | 5 | 0 | 0 | 0 | 6 | 1 | 2 | 4.77 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 13 | 13 | 5 | 7 | 7.29 | .370 | 1.74 | 11.6 | 4.1 | 5.0 | 84.0 | 108 | 75 | 68 | 17 | 38 | 47 | 2 | 0 | 0 | 0 | 3 | 2 | 3 | 5.94 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 35 | 0 | 1 | 1 | 2.79 | .263 | 1.07 | 6.9 | 2.8 | 9.9 | 42.0 | 32 | 13 | 13 | 8 | 13 | 46 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 69 | 23 | 0 | 1 | 1 | 3.74 | .286 | 1.15 | 6.9 | 3.9 | 8.6 | 21.2 | 16 | 10 | 9 | 1 | 9 | 20 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.14 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 16 | 0 | 0 | 0 | 4.35 | .295 | 1.26 | 9.9 | 1.8 | 7.7 | 20.2 | 22 | 10 | 10 | 4 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 6 | 0 | 1 | 2 | 2.70 | .322 | 1.43 | 9.0 | 4.2 | 4.2 | 13.1 | 13 | 4 | 4 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.46 |