| SP | Tiant, L.Tiant, Luis † # >> | 28 | 1968 | R | 97 | 19 | 19 | 9 | 6 | 3.08 | .285 | 1.18 | 7.2 | 3.4 | 7.9 | 152.0 | 122 | 54 | 52 | 12 | 58 | 133 | 6 | 0 | 0 | 2 | 12 | 2 | 2 | 3.46 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 18 | 18 | 5 | 11 | 4.90 | .324 | 1.43 | 10.2 | 2.7 | 5.2 | 141.1 | 160 | 81 | 77 | 20 | 42 | 81 | 8 | 0 | 0 | 1 | 8 | 1 | 2 | 4.61 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 16 | 16 | 6 | 6 | 3.96 | .316 | 1.36 | 8.6 | 3.7 | 3.4 | 102.1 | 97 | 48 | 45 | 9 | 42 | 39 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.71 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 39 | 0 | 3 | 5 | 3.59 | .325 | 1.43 | 7.3 | 5.7 | 6.3 | 47.2 | 38 | 20 | 19 | 1 | 30 | 33 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 3.85 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 34 | 0 | 2 | 2 | 4.55 | .321 | 1.38 | 8.4 | 4.3 | 8.7 | 29.2 | 27 | 16 | 15 | 5 | 14 | 28 | 0 | 5 | 4 | 0 | 0 | 1 | 1 | 4.86 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 1 | 1 | 0 | 0 | 1.42 | .136 | 0.47 | 4.5 | 0.0 | 9.0 | 6.1 | 3 | 1 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1.00 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 4 | 0 | 0 | 1 | 3.60 | .318 | 1.40 | 9.0 | 3.6 | 5.4 | 5.0 | 5 | 2 | 2 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.60 |