| SP | Kershaw, C.Kershaw, Clayton $ >> | 28 | 2016 | L | 99 | 19 | 19 | 8 | 8 | 3.93 | .295 | 1.25 | 9.0 | 2.3 | 7.3 | 139.2 | 139 | 67 | 61 | 21 | 35 | 113 | 4 | 0 | 0 | 1 | 10 | 1 | 7 | 4.12 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 18 | 18 | 9 | 5 | 4.59 | .308 | 1.32 | 9.2 | 2.7 | 6.8 | 117.2 | 120 | 64 | 60 | 17 | 35 | 89 | 2 | 0 | 0 | 0 | 8 | 2 | 0 | 4.32 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 18 | 18 | 8 | 5 | 4.06 | .285 | 1.17 | 7.8 | 2.7 | 7.7 | 128.2 | 111 | 58 | 58 | 22 | 39 | 110 | 4 | 0 | 0 | 1 | 8 | 4 | 3 | 4.52 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 17 | 17 | 4 | 8 | 5.76 | .330 | 1.46 | 9.4 | 3.8 | 5.0 | 118.2 | 123 | 81 | 76 | 16 | 50 | 65 | 3 | 0 | 0 | 1 | 3 | 2 | 2 | 4.98 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 28 | 0 | 4 | 2 | 2.41 | .223 | 0.86 | 5.7 | 2.2 | 9.0 | 33.2 | 21 | 9 | 9 | 5 | 8 | 33 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 3.70 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 17 | 0 | 0 | 3 | 6.61 | .347 | 1.59 | 9.6 | 5.1 | 11.3 | 16.1 | 17 | 12 | 12 | 1 | 9 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.00 |
| RP | Bautista, F.Bautista, Félix $ >> | 28 | 2023 | R | 75 | 16 | 0 | 2 | 0 | 3.45 | .288 | 1.21 | 7.2 | 4.2 | 7.8 | 15.2 | 12 | 6 | 6 | 3 | 7 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 5.27 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 15 | 0 | 0 | 0 | 1.89 | .321 | 1.42 | 6.6 | 6.2 | 3.8 | 19.0 | 14 | 5 | 4 | 0 | 13 | 8 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.21 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 13 | 0 | 2 | 2 | 4.50 | .277 | 1.15 | 6.3 | 4.1 | 8.3 | 60.0 | 42 | 31 | 30 | 7 | 27 | 55 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.03 |