| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 28 | 28 | 8 | 11 | 3.88 | .308 | 1.30 | 7.9 | 3.8 | 10.8 | 190.0 | 167 | 83 | 82 | 19 | 80 | 229 | 0 | 0 | 0 | 0 | 17 | 7 | 2 | 3.26 |
| SP | Carrasco, C.Carrasco, Carlos >> | 27 | 2014 | R | 83 | 27 | 27 | 0 | 7 | 5.34 | .322 | 1.37 | 9.8 | 2.6 | 9.0 | 97.2 | 106 | 58 | 58 | 13 | 28 | 97 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 3.76 |
| SP | Buchholz, C.Buchholz, Clay † # >> | 29 | 2013 | R | 81 | 27 | 27 | 14 | 8 | 3.93 | .324 | 1.41 | 9.6 | 3.1 | 6.8 | 192.1 | 205 | 88 | 84 | 20 | 66 | 146 | 1 | 0 | 0 | 1 | 15 | 5 | 2 | 3.94 |
| SP | Oswalt, R.Oswalt, Roy # >> | 33 | 2010 | R | 68 | 27 | 27 | 9 | 10 | 5.89 | .342 | 1.54 | 10.2 | 3.7 | 7.9 | 169.2 | 191 | 115 | 111 | 29 | 70 | 148 | 0 | 0 | 0 | 0 | 10 | 4 | 4 | 4.79 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 60 | 26 | 26 | 4 | 12 | 7.35 | .369 | 1.67 | 10.8 | 4.2 | 8.2 | 153.0 | 184 | 128 | 125 | 31 | 72 | 140 | 0 | 0 | 0 | 0 | 8 | 12 | 9 | 5.45 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 73 | 0 | 11 | 4 | 4.42 | .330 | 1.42 | 9.3 | 3.6 | 9.8 | 97.2 | 100 | 51 | 48 | 12 | 39 | 106 | 0 | 4 | 1 | 0 | 0 | 5 | 5 | 3.78 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 84 | 71 | 0 | 5 | 5 | 3.02 | .277 | 1.12 | 7.7 | 2.3 | 10.3 | 92.1 | 79 | 33 | 31 | 9 | 24 | 105 | 0 | 10 | 3 | 0 | 0 | 3 | 5 | 2.87 |
| RP | Frieri, E.Frieri, Ernesto >> | 26 | 2012 | R | 68 | 63 | 0 | 5 | 5 | 3.29 | .309 | 1.34 | 6.8 | 5.4 | 10.5 | 76.2 | 57 | 28 | 28 | 11 | 46 | 89 | 0 | 8 | 6 | 0 | 0 | 0 | 0 | 4.36 |
| RP | Jeffress, J.Jeffress, Jeremy >> | 30 | 2018 | R | 41 | 47 | 0 | 1 | 4 | 4.18 | .306 | 1.21 | 7.9 | 3.1 | 8.4 | 56.0 | 49 | 27 | 26 | 8 | 19 | 52 | 0 | 8 | 2 | 0 | 0 | 6 | 1 | 4.34 |
| SP | Bieber, S.Bieber, Shane >> | 24 | 2019 | R | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Castillo, L.Castillo, Luis >> | 26 | 2019 | R | 50 | 2 | 0 | 0 | 0 | 5.40 | .444 | 2.40 | 18.0 | 18.0 | 9.0 | 1.2 | 2 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| SP | Teheran, J.Teheran, Julio >> | 23 | 2014 | R | 41 | 18 | 0 | 3 | 4 | 6.66 | .354 | 1.64 | 12.4 | 2.6 | 7.5 | 24.1 | 33 | 18 | 18 | 5 | 7 | 20 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.92 |