| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 18 | 18 | 7 | 6 | 3.57 | .300 | 1.26 | 8.4 | 3.0 | 9.7 | 126.0 | 117 | 53 | 50 | 14 | 42 | 136 | 4 | 0 | 0 | 1 | 12 | 3 | 3 | 3.36 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 74 | 17 | 17 | 6 | 5 | 5.40 | .325 | 1.39 | 10.0 | 2.6 | 8.8 | 73.1 | 81 | 49 | 44 | 11 | 21 | 71 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 4.04 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 56 | 17 | 17 | 10 | 3 | 4.47 | .316 | 1.36 | 7.9 | 4.4 | 6.5 | 106.2 | 93 | 57 | 53 | 26 | 52 | 77 | 1 | 0 | 0 | 1 | 8 | 3 | 4 | 6.29 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 16 | 16 | 6 | 6 | 5.14 | .339 | 1.52 | 9.0 | 4.7 | 9.9 | 98.0 | 98 | 56 | 56 | 20 | 51 | 108 | 0 | 0 | 0 | 0 | 6 | 2 | 6 | 5.07 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 16 | 16 | 5 | 5 | 5.77 | .339 | 1.51 | 10.1 | 3.6 | 8.0 | 96.2 | 108 | 62 | 62 | 20 | 38 | 85 | 1 | 0 | 0 | 0 | 6 | 3 | 1 | 5.22 |
| RP | Gallegos, G.Gallegos, Giovanny † >> | 27 | 2019 | R | 77 | 48 | 0 | 3 | 3 | 4.50 | .290 | 1.17 | 6.8 | 3.7 | 10.9 | 58.0 | 44 | 29 | 29 | 8 | 24 | 70 | 0 | 12 | 2 | 0 | 0 | 3 | 2 | 3.78 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 34 | 0 | 2 | 3 | 5.31 | .355 | 1.61 | 11.6 | 3.0 | 9.9 | 42.1 | 54 | 27 | 25 | 10 | 14 | 46 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 5.05 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 52 | 29 | 0 | 1 | 2 | 4.45 | .331 | 1.39 | 8.7 | 3.9 | 8.7 | 32.1 | 31 | 16 | 16 | 5 | 14 | 31 | 0 | 4 | 0 | 0 | 0 | 3 | 1 | 4.69 |