| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 30 | 30 | 11 | 12 | 4.21 | .295 | 1.21 | 8.1 | 2.8 | 6.7 | 205.0 | 184 | 100 | 96 | 30 | 64 | 152 | 4 | 0 | 0 | 0 | 19 | 9 | 7 | 4.49 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 26 | 26 | 6 | 13 | 5.15 | .345 | 1.57 | 10.3 | 3.8 | 8.2 | 164.1 | 188 | 104 | 94 | 28 | 70 | 150 | 2 | 0 | 0 | 0 | 11 | 2 | 3 | 4.71 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 28 | 27 | 5 | 16 | 6.33 | .353 | 1.61 | 10.9 | 3.6 | 6.8 | 175.0 | 212 | 132 | 123 | 31 | 70 | 133 | 4 | 0 | 0 | 0 | 7 | 5 | 6 | 5.07 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 52 | 0 | 3 | 6 | 5.34 | .318 | 1.38 | 9.2 | 3.4 | 11.1 | 55.2 | 56 | 36 | 33 | 13 | 21 | 68 | 0 | 24 | 7 | 0 | 0 | 1 | 1 | 4.80 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 59 | 0 | 2 | 1 | 3.39 | .295 | 1.21 | 7.1 | 3.9 | 12.1 | 63.2 | 50 | 24 | 24 | 8 | 27 | 85 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 3.38 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 46 | 0 | 2 | 3 | 4.50 | .313 | 1.30 | 8.2 | 3.5 | 10.0 | 46.0 | 42 | 25 | 23 | 5 | 18 | 51 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 3.57 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 36 | 0 | 3 | 3 | 4.65 | .344 | 1.52 | 8.6 | 5.4 | 12.2 | 40.2 | 38 | 21 | 21 | 7 | 24 | 54 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 4.53 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 35 | 0 | 3 | 0 | 2.63 | .297 | 1.24 | 7.5 | 3.7 | 5.0 | 41.0 | 34 | 12 | 12 | 4 | 17 | 23 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.46 |