| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 95 | 29 | 29 | 10 | 12 | 3.27 | .273 | 1.10 | 7.8 | 2.1 | 9.2 | 214.2 | 185 | 83 | 78 | 19 | 51 | 218 | 9 | 0 | 0 | 3 | 20 | 6 | 3 | 2.92 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 29 | 29 | 8 | 12 | 3.90 | .315 | 1.35 | 8.6 | 3.6 | 9.5 | 182.1 | 174 | 85 | 79 | 19 | 73 | 192 | 1 | 0 | 0 | 0 | 15 | 5 | 6 | 3.53 |
| SP | Wilson, D.Wilson, Don # >> | 26 | 1971 | R | 59 | 28 | 28 | 12 | 13 | 4.55 | .298 | 1.27 | 8.4 | 3.0 | 6.0 | 190.0 | 178 | 103 | 96 | 28 | 63 | 126 | 3 | 0 | 0 | 0 | 14 | 1 | 2 | 4.60 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 57 | 27 | 27 | 8 | 12 | 5.79 | .330 | 1.48 | 9.2 | 4.1 | 9.7 | 157.0 | 161 | 103 | 101 | 34 | 71 | 170 | 0 | 0 | 0 | 0 | 10 | 0 | 7 | 5.01 |
| RP | Edwards, C.Edwards, Carl # >> | 24 | 2016 | R | 93 | 74 | 0 | 0 | 7 | 4.85 | .342 | 1.49 | 7.2 | 6.2 | 10.2 | 91.0 | 73 | 51 | 49 | 12 | 63 | 103 | 0 | 8 | 7 | 0 | 0 | 6 | 5 | 4.73 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 62 | 68 | 0 | 4 | 3 | 4.33 | .314 | 1.36 | 8.4 | 4.0 | 9.3 | 72.2 | 67 | 39 | 35 | 10 | 32 | 74 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 4.13 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 55 | 51 | 0 | 4 | 7 | 3.02 | .248 | 0.97 | 6.5 | 2.4 | 10.2 | 65.2 | 47 | 25 | 22 | 11 | 17 | 74 | 0 | 4 | 1 | 0 | 0 | 1 | 4 | 3.75 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 40 | 35 | 0 | 4 | 1 | 3.92 | .292 | 1.21 | 8.2 | 2.9 | 8.6 | 43.2 | 39 | 21 | 19 | 6 | 14 | 41 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.95 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 16 | 0 | 1 | 2 | 3.72 | .348 | 1.50 | 8.1 | 5.7 | 9.5 | 19.1 | 17 | 8 | 8 | 3 | 12 | 20 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 5.16 |