| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 36 | 36 | 16 | 10 | 4.01 | .290 | 1.20 | 7.9 | 2.8 | 8.0 | 231.1 | 204 | 109 | 103 | 32 | 73 | 205 | 1 | 0 | 0 | 0 | 21 | 6 | 3 | 4.05 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 35 | 35 | 12 | 11 | 5.07 | .323 | 1.40 | 9.7 | 3.0 | 7.8 | 207.2 | 222 | 127 | 117 | 39 | 68 | 179 | 2 | 0 | 0 | 0 | 16 | 7 | 5 | 4.81 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 3 | 1 | 0 | 0 | 3.68 | .267 | 1.09 | 7.7 | 2.6 | 9.0 | 7.1 | 6 | 3 | 3 | 0 | 2 | 7 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1.86 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 65 | 0 | 3 | 5 | 3.44 | .277 | 1.10 | 7.1 | 2.8 | 9.5 | 68.0 | 54 | 27 | 26 | 10 | 21 | 72 | 0 | 45 | 3 | 0 | 0 | 3 | 0 | 3.85 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 49 | 0 | 0 | 2 | 4.97 | .309 | 1.33 | 8.7 | 3.3 | 9.6 | 70.2 | 68 | 41 | 39 | 12 | 26 | 75 | 0 | 1 | 7 | 0 | 0 | 1 | 0 | 4.24 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 81 | 0 | 5 | 6 | 4.60 | .334 | 1.49 | 9.2 | 4.3 | 9.5 | 78.1 | 80 | 43 | 40 | 16 | 37 | 82 | 0 | 2 | 3 | 0 | 0 | 1 | 5 | 5.03 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 52 | 0 | 4 | 2 | 3.67 | .297 | 1.24 | 9.0 | 2.2 | 7.5 | 49.0 | 49 | 21 | 20 | 6 | 12 | 41 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 3.71 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 28 | 0 | 1 | 0 | 2.79 | .298 | 1.28 | 6.2 | 5.3 | 9.9 | 29.0 | 20 | 9 | 9 | 2 | 17 | 32 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.45 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 63 | 26 | 0 | 2 | 2 | 3.71 | .259 | 1.05 | 7.6 | 2.1 | 12.8 | 26.2 | 22 | 12 | 11 | 6 | 6 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.85 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 32 | 32 | 16 | 10 | 3.68 | .302 | 1.26 | 7.6 | 3.8 | 6.4 | 215.1 | 181 | 96 | 88 | 24 | 91 | 154 | 7 | 0 | 0 | 1 | 21 | 8 | 6 | 4.40 |
| SP | Brown, K.Brown, Kevin # >> | 31 | 1996 | R | 67 | 31 | 31 | 10 | 15 | 5.06 | .328 | 1.44 | 9.9 | 3.1 | 5.5 | 199.1 | 220 | 117 | 112 | 18 | 68 | 121 | 4 | 0 | 0 | 0 | 15 | 4 | 3 | 4.05 |