| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 36 | 36 | 10 | 13 | 3.45 | .274 | 1.13 | 7.9 | 2.2 | 9.6 | 237.1 | 208 | 91 | 91 | 31 | 59 | 252 | 1 | 0 | 0 | 0 | 25 | 2 | 0 | 3.35 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 34 | 34 | 12 | 14 | 4.47 | .290 | 1.19 | 7.8 | 3.0 | 7.7 | 211.1 | 182 | 106 | 105 | 41 | 70 | 180 | 1 | 0 | 0 | 1 | 16 | 7 | 5 | 4.91 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 83 | 34 | 34 | 11 | 15 | 4.27 | .301 | 1.25 | 7.7 | 3.6 | 7.6 | 208.2 | 177 | 99 | 99 | 27 | 84 | 175 | 1 | 0 | 0 | 1 | 19 | 8 | 3 | 4.33 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 33 | 33 | 16 | 12 | 4.52 | .309 | 1.32 | 8.6 | 3.2 | 6.1 | 203.0 | 194 | 106 | 102 | 26 | 73 | 137 | 2 | 0 | 0 | 1 | 18 | 5 | 8 | 4.47 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 33 | 31 | 15 | 9 | 4.16 | .293 | 1.23 | 8.1 | 2.9 | 5.8 | 236.0 | 213 | 110 | 109 | 26 | 77 | 152 | 4 | 0 | 0 | 1 | 17 | 4 | 4 | 4.17 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 92 | 103 | 0 | 6 | 3 | 2.45 | .273 | 1.10 | 5.5 | 4.5 | 11.3 | 80.2 | 49 | 22 | 22 | 7 | 40 | 100 | 0 | 1 | 3 | 0 | 0 | 2 | 3 | 3.21 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 105 | 0 | 6 | 1 | 3.38 | .277 | 1.13 | 7.6 | 2.5 | 9.5 | 117.1 | 99 | 44 | 44 | 17 | 33 | 124 | 0 | 3 | 2 | 0 | 0 | 3 | 0 | 3.69 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 78 | 0 | 4 | 2 | 3.04 | .276 | 1.11 | 6.5 | 3.5 | 9.1 | 71.0 | 51 | 24 | 24 | 6 | 28 | 72 | 0 | 2 | 4 | 0 | 0 | 2 | 0 | 3.34 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 52 | 0 | 2 | 5 | 3.24 | .275 | 1.14 | 7.5 | 2.9 | 9.4 | 66.2 | 55 | 24 | 24 | 7 | 21 | 69 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.24 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 78 | 0 | 6 | 6 | 2.36 | .229 | 0.87 | 4.9 | 3.0 | 11.4 | 87.2 | 47 | 23 | 23 | 11 | 29 | 110 | 0 | 41 | 6 | 0 | 0 | 2 | 5 | 3.18 |