| SP | Harrison, M.Harrison, Matt # >> | 26 | 2011 | L | 17 | 8 | 8 | 2 | 2 | 6.17 | .380 | 1.82 | 12.6 | 3.9 | 7.7 | 42.1 | 59 | 32 | 29 | 10 | 18 | 36 | 0 | 0 | 0 | 0 | 3 | 1 | 3 | 5.74 |
| SP | Blyleven, B.Blyleven, Bert # >> | 26 | 1977 | R | 80 | 25 | 25 | 9 | 11 | 3.78 | .266 | 1.04 | 7.5 | 1.9 | 6.8 | 178.2 | 148 | 76 | 75 | 28 | 37 | 134 | 5 | 0 | 0 | 1 | 15 | 9 | 1 | 4.31 |
| SP | Wilson, C.Wilson, C.J. >> | 31 | 2011 | L | 42 | 24 | 24 | 11 | 9 | 3.98 | .297 | 1.21 | 7.9 | 3.0 | 7.2 | 158.1 | 139 | 72 | 70 | 18 | 53 | 126 | 1 | 0 | 0 | 0 | 14 | 9 | 8 | 4.06 |
| SP | Ogando, A.Ogando, Alexi >> | 27 | 2011 | R | 50 | 23 | 22 | 8 | 5 | 5.01 | .337 | 1.43 | 9.4 | 3.6 | 5.8 | 118.2 | 123 | 69 | 66 | 19 | 47 | 76 | 0 | 0 | 0 | 0 | 7 | 11 | 1 | 5.28 |
| SU | Feliz, N.Feliz, Neftali >> | 23 | 2011 | R | 50 | 51 | 0 | 2 | 1 | 4.44 | .301 | 1.23 | 6.0 | 5.3 | 5.6 | 48.2 | 32 | 26 | 24 | 8 | 28 | 30 | 0 | 1 | 4 | 0 | 0 | 3 | 2 | 5.85 |
| RP | Benoit, J.Benoit, Joaquin >> | 28 | 2005 | R | 36 | 33 | 0 | 2 | 5 | 3.44 | .311 | 1.32 | 8.1 | 3.8 | 7.1 | 52.1 | 47 | 20 | 20 | 6 | 22 | 41 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.31 |
| RP | Uehara, K.Uehara, Koji >> | 36 | 2011 | R | 100 | 47 | 0 | 2 | 1 | 4.25 | .284 | 1.17 | 8.1 | 2.6 | 9.8 | 48.2 | 43 | 27 | 23 | 6 | 14 | 52 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.40 |