| SP | Severino, L.Severino, Luis >> | 28 | 2022 | R | 94 | 33 | 33 | 17 | 7 | 2.95 | .265 | 1.06 | 6.5 | 3.0 | 10.0 | 198.1 | 143 | 67 | 65 | 21 | 67 | 220 | 1 | 0 | 0 | 0 | 19 | 4 | 1 | 3.23 |
| SP | Cortes Jr., N.Cortes Jr., Nestor † >> | 27 | 2022 | L | 96 | 31 | 31 | 18 | 4 | 3.07 | .268 | 1.06 | 7.3 | 2.2 | 9.4 | 199.2 | 162 | 69 | 68 | 24 | 49 | 208 | 0 | 0 | 0 | 0 | 21 | 8 | 2 | 3.34 |
| SP | Montgomery, J.Montgomery, Jordan >> | 29 | 2022 | L | 61 | 17 | 16 | 7 | 6 | 5.38 | .341 | 1.50 | 10.7 | 2.8 | 5.9 | 95.1 | 113 | 66 | 57 | 10 | 30 | 62 | 0 | 0 | 0 | 0 | 6 | 5 | 1 | 4.17 |
| SU | Holmes, C.Holmes, Clay >> | 29 | 2022 | R | 80 | 43 | 0 | 2 | 2 | 3.22 | .301 | 1.25 | 7.9 | 3.4 | 7.9 | 50.1 | 44 | 18 | 18 | 5 | 19 | 44 | 0 | 2 | 4 | 0 | 0 | 2 | 1 | 3.80 |
| RP | Chapman, A.Chapman, Aroldis >> | 34 | 2022 | L | 48 | 72 | 0 | 5 | 3 | 2.97 | .305 | 1.28 | 5.7 | 6.0 | 9.8 | 57.2 | 36 | 28 | 19 | 4 | 38 | 62 | 0 | 1 | 2 | 0 | 0 | 2 | 15 | 3.84 |
| RP | Arroyo, L.Arroyo, Luis >> | 34 | 1961 | L | 61 | 47 | 0 | 2 | 1 | 2.86 | .292 | 1.24 | 6.8 | 4.5 | 6.4 | 28.1 | 21 | 11 | 9 | 1 | 14 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.54 |
| CL | Peralta, W.Peralta, Wandy † >> | 30 | 2022 | L | 70 | 58 | 0 | 5 | 3 | 1.76 | .218 | 0.82 | 5.0 | 2.4 | 5.5 | 56.1 | 31 | 14 | 11 | 4 | 15 | 34 | 0 | 39 | 2 | 0 | 0 | 1 | 0 | 3.57 |
| RP | Shawkey, B.Shawkey, Bob >> | 37 | 1927 | R | 20 | 52 | 0 | 4 | 1 | 4.15 | .335 | 1.49 | 8.8 | 4.7 | 5.6 | 56.1 | 55 | 32 | 26 | 8 | 29 | 35 | 0 | 1 | 5 | 0 | 0 | 1 | 3 | 5.21 |
| RP | German, D.German, Domingo # >> | 29 | 2022 | R | 33 | 53 | 0 | 3 | 3 | 4.63 | .307 | 1.31 | 7.7 | 4.1 | 6.3 | 70.0 | 60 | 44 | 36 | 12 | 32 | 49 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.24 |
| SP | Shocker, U.Shocker, Urban # >> | 37 | 1927 | R | 22 | 5 | 5 | 2 | 2 | 7.14 | .336 | 1.52 | 10.9 | 2.8 | 6.2 | 29.0 | 35 | 26 | 23 | 7 | 9 | 20 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.69 |