| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 20 | 20 | 11 | 2 | 3.38 | .315 | 1.36 | 7.8 | 4.5 | 8.5 | 119.2 | 103 | 46 | 45 | 6 | 60 | 112 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 3.34 |
| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 19 | 19 | 12 | 5 | 3.25 | .267 | 1.06 | 7.4 | 2.1 | 8.3 | 144.0 | 119 | 52 | 52 | 10 | 34 | 133 | 6 | 0 | 0 | 2 | 12 | 4 | 2 | 2.85 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 19 | 19 | 7 | 10 | 4.84 | .303 | 1.28 | 9.1 | 2.4 | 4.1 | 134.0 | 136 | 74 | 72 | 15 | 35 | 61 | 6 | 0 | 0 | 1 | 10 | 4 | 2 | 4.42 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 19 | 19 | 12 | 4 | 4.25 | .318 | 1.37 | 9.3 | 3.1 | 5.4 | 139.2 | 143 | 72 | 66 | 16 | 48 | 84 | 1 | 0 | 0 | 0 | 10 | 4 | 3 | 4.41 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 39 | 0 | 1 | 0 | 1.47 | .236 | 0.93 | 5.5 | 3.0 | 6.5 | 36.2 | 22 | 6 | 6 | 0 | 12 | 26 | 0 | 32 | 1 | 0 | 0 | 0 | 0 | 2.56 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 94 | 45 | 0 | 2 | 3 | 2.04 | .279 | 1.16 | 8.0 | 2.6 | 8.0 | 35.1 | 31 | 8 | 8 | 1 | 10 | 31 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 43 | 0 | 0 | 0 | 1.62 | .237 | 0.93 | 6.5 | 1.9 | 7.6 | 33.1 | 24 | 8 | 6 | 2 | 7 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 2.73 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 29 | 0 | 1 | 1 | 4.87 | .307 | 1.33 | 11.3 | 0.9 | 8.6 | 20.1 | 25 | 12 | 11 | 3 | 2 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.35 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 8 | 0 | 1 | 0 | 4.21 | .280 | 1.13 | 8.3 | 2.2 | 6.1 | 25.2 | 23 | 12 | 12 | 3 | 6 | 17 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.04 |