| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 21 | 21 | 8 | 11 | 3.52 | .270 | 1.10 | 8.0 | 2.0 | 5.7 | 156.0 | 138 | 63 | 61 | 18 | 34 | 98 | 6 | 0 | 0 | 3 | 12 | 1 | 1 | 3.92 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 20 | 20 | 5 | 8 | 6.77 | .380 | 1.82 | 12.0 | 4.4 | 7.1 | 109.0 | 145 | 89 | 82 | 13 | 53 | 86 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 4.49 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 19 | 19 | 7 | 9 | 5.60 | .361 | 1.66 | 11.3 | 3.7 | 5.9 | 109.1 | 137 | 76 | 68 | 19 | 45 | 72 | 2 | 0 | 0 | 0 | 8 | 3 | 6 | 5.27 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 19 | 19 | 4 | 7 | 5.68 | .340 | 1.53 | 8.5 | 5.4 | 8.1 | 88.2 | 83 | 57 | 56 | 17 | 53 | 79 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.56 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 49 | 0 | 3 | 3 | 4.44 | .318 | 1.37 | 8.4 | 3.9 | 7.6 | 73.0 | 68 | 43 | 36 | 10 | 32 | 62 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.48 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 46 | 0 | 1 | 1 | 3.17 | .327 | 1.46 | 6.9 | 6.4 | 9.3 | 59.2 | 45 | 26 | 21 | 4 | 42 | 61 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.95 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 3 | 0 | 0 | 0 | 1.80 | .211 | 0.80 | 5.4 | 1.8 | 5.4 | 5.0 | 3 | 1 | 1 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 27 | 0 | 5 | 2 | 3.63 | .350 | 1.60 | 9.9 | 4.4 | 3.9 | 57.0 | 63 | 30 | 23 | 5 | 28 | 25 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 4.79 |