| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 14 | 14 | 4 | 7 | 5.36 | .330 | 1.47 | 10.3 | 2.9 | 5.4 | 94.0 | 108 | 56 | 56 | 16 | 30 | 56 | 2 | 0 | 0 | 0 | 5 | 1 | 1 | 5.01 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 13 | 3 | 9 | 4.76 | .322 | 1.43 | 9.4 | 3.4 | 4.6 | 87.0 | 91 | 52 | 46 | 9 | 33 | 44 | 2 | 0 | 0 | 1 | 7 | 0 | 1 | 4.47 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 35 | 0 | 3 | 1 | 4.70 | .291 | 1.23 | 7.8 | 3.4 | 6.6 | 53.2 | 46 | 28 | 28 | 3 | 20 | 39 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.40 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 62 | 35 | 0 | 3 | 1 | 3.31 | .262 | 1.06 | 6.5 | 3.2 | 7.2 | 51.2 | 37 | 21 | 19 | 8 | 18 | 41 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.49 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 49 | 28 | 0 | 0 | 2 | 3.90 | .308 | 1.34 | 9.0 | 3.3 | 6.3 | 27.2 | 27 | 12 | 12 | 4 | 10 | 19 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.63 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 62 | 3 | 3 | 1 | 1 | 8.82 | .395 | 1.96 | 13.5 | 4.5 | 5.6 | 16.1 | 24 | 16 | 16 | 1 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.06 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 49 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 15 | 0 | 1 | 4 | 3.38 | .281 | 1.17 | 9.9 | 0.9 | 3.4 | 21.1 | 23 | 8 | 8 | 4 | 2 | 8 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.00 |