| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 13 | 13 | 7 | 6 | 3.50 | .264 | 1.07 | 7.1 | 2.5 | 9.3 | 103.0 | 81 | 42 | 40 | 10 | 29 | 106 | 5 | 0 | 0 | 0 | 6 | 1 | 0 | 3.08 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 13 | 13 | 8 | 3 | 3.64 | .290 | 1.20 | 7.9 | 2.9 | 7.3 | 84.0 | 74 | 34 | 34 | 9 | 27 | 68 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 3.81 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 13 | 13 | 3 | 7 | 6.15 | .330 | 1.48 | 10.6 | 2.7 | 4.8 | 89.1 | 105 | 62 | 61 | 11 | 27 | 47 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.46 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 21 | 0 | 0 | 2 | 3.68 | .305 | 1.32 | 9.0 | 2.9 | 8.2 | 22.0 | 22 | 9 | 9 | 3 | 7 | 20 | 0 | 15 | 1 | 0 | 0 | 0 | 1 | 3.91 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 14 | 0 | 0 | 0 | 6.23 | .339 | 1.46 | 9.0 | 4.2 | 7.6 | 13.0 | 13 | 9 | 9 | 2 | 6 | 11 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.92 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 8 | 0 | 0 | 0 | 7.11 | .345 | 1.58 | 10.5 | 4.5 | 7.5 | 6.1 | 7 | 5 | 5 | 4 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.50 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 5 | 0 | 0 | 0 | 0.00 | .320 | 1.24 | 1.8 | 10.8 | 7.2 | 5.2 | 1 | 0 | 0 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.60 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 12 | 0 | 0 | 0 | 4.05 | .273 | 1.13 | 6.9 | 3.5 | 8.3 | 13.1 | 10 | 6 | 6 | 3 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.31 |