| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 20 | 20 | 6 | 12 | 4.41 | .299 | 1.27 | 9.1 | 2.4 | 8.5 | 134.2 | 135 | 69 | 66 | 28 | 36 | 126 | 1 | 0 | 0 | 0 | 12 | 1 | 3 | 4.66 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 19 | 19 | 3 | 12 | 5.77 | .326 | 1.41 | 9.3 | 3.4 | 8.8 | 107.2 | 111 | 72 | 69 | 14 | 41 | 105 | 1 | 0 | 0 | 1 | 8 | 4 | 1 | 4.00 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 18 | 18 | 5 | 9 | 7.07 | .372 | 1.78 | 11.7 | 4.4 | 6.0 | 105.2 | 137 | 89 | 83 | 23 | 51 | 70 | 3 | 0 | 0 | 0 | 5 | 0 | 6 | 5.97 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 53 | 0 | 2 | 0 | 2.54 | .277 | 1.09 | 5.5 | 4.4 | 9.0 | 49.2 | 30 | 20 | 14 | 3 | 24 | 49 | 0 | 1 | 1 | 0 | 0 | 3 | 3 | 3.45 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 37 | 0 | 0 | 0 | 4.75 | .302 | 1.30 | 9.2 | 2.6 | 7.2 | 41.2 | 42 | 22 | 22 | 5 | 12 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.85 |
| CL | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 74 | 39 | 0 | 0 | 6 | 5.94 | .374 | 1.76 | 11.5 | 4.5 | 9.0 | 36.1 | 46 | 27 | 24 | 1 | 18 | 36 | 0 | 19 | 3 | 0 | 0 | 1 | 4 | 2.94 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 37 | 0 | 1 | 1 | 4.54 | .313 | 1.34 | 8.6 | 3.7 | 8.3 | 41.2 | 39 | 21 | 21 | 3 | 17 | 38 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.41 |
| SP | Carpenter, C.Carpenter, Chris >> | 30 | 2005 | R | 19 | 11 | 0 | 1 | 3 | 15.32 | .500 | 3.00 | 18.0 | 9.8 | 6.8 | 12.1 | 24 | 21 | 21 | 3 | 13 | 9 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 8.00 |